Evidence map›Paper›PMID 42819034›Full record

ArticleNanoscale advances2026

Near-infrared light-controlled catalytic hairpin assembly fluorescent biosensor for the sensitive and specific detection of fibroblast activation protein.

Jiayi Wu, Xingchun Zheng, Jinhua Huang, En Chen

Abstract read
In one paragraph

Article in Nanoscale advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jiayi WuDepartment of Cardiology, Fujian Medical University Union Hospital, Fujian Cardiovascular Medicine Center, Fujian Institute of Coronary Artery Disease, Fujian Cardiovascular Research Center, Fujian Medical University Heart Center Fuzhou 350001 China wjym6@163.com.ORCID https://orcid.org/0009-0006-3234-8580
Xingchun ZhengDepartment of Cardiology, Fujian Medical University Union Hospital, Fujian Cardiovascular Medicine Center, Fujian Institute of Coronary Artery Disease, Fujian Cardiovascular Research Center, Fujian Medical University Heart Center Fuzhou 350001 China wjym6@163.com.
Jinhua HuangDepartment of Cardiology, Fujian Medical University Union Hospital, Fujian Cardiovascular Medicine Center, Fujian Institute of Coronary Artery Disease, Fujian Cardiovascular Research Center, Fujian Medical University Heart Center Fuzhou 350001 China wjym6@163.com.
En ChenDepartment of Cardiology, Fujian Medical University Union Hospital, Fujian Cardiovascular Medicine Center, Fujian Institute of Coronary Artery Disease, Fujian Cardiovascular Research Center, Fujian Medical University Heart Center Fuzhou 350001 China wjym6@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibroblast activation protein (FAP) is significantly upregulated in activated cardiac fibroblasts after myocardial infarction, and its serum concentration is negatively correlated with cardiac function, infarct size, and ischemia score. It is an ideal biomarker for early diagnosis and prognosis evaluation of cardiovascular disease. In this work, a fluorescent biosensor based on a near-infrared light-controlled catalytic hairpin assembly (CHA) signal amplification strategy was developed for highly sensitive and specific detection of FAP. First, upconversion nanoparticles (UCNPs) are synthesized, and then the surface of the UCNP is modified with sodium citrate

Identifiers

PMID42819034
PMCPMC13624721

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.