ArticleFrontiers in urology2026
Case Report: cytoreductive prostatectomy after platinum-etoposide chemotherapy for
Article in Frontiers in urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To describe the diagnostic challenges, treatment response, and potential benefits and risks of cytoreductive surgery in Methods: We retrospectively reviewed the clinical course of one patient with Results: A 50-year-old man presented in June 2022 with progressive dysuria for more than 1 year and acute urinary retention for 1 day. Transurethral resection of the prostate (TURP) was performed to relieve obstruction, and review of the specimen supported SCNEC. Staging Conclusion: EP can produce substantial but temporary regression in metastatic prostatic SCNEC. This case did not establish a survival benefit from surgery, although temporary relief of urinary obstruction was reported. Systemic therapy should remain the priority, and surgery should be limited to carefully selected local-control or palliative indications.
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