ArticlemedRxiv : the preprint server for health sciences2026
Childhood Correlates of Genetic Propensity to Personality Traits.
Margaret L Clapp Sullivan, Alex P Miller, Emma C Johnson, Nicole R Karcher, Sarah E Paul, Joshua J Jackson, Ryan Bogdan, Arpana Agrawal
Abstract readPreprint
In one paragraphArticle in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
8 authors.
Alex P MillerDepartment of Psychiatry, Indiana University School of Medicine.
Nicole R KarcherDepartment of Psychiatry, Washington University School of Medicine.
Sarah E PaulCenter for Precision Psychiatry, Department of Psychiatry, Massachusetts General Hospital.ORCID 0000-0003-0320-7907 Joshua J JacksonDepartment of Psychological & Brain Sciences, Washington University in St. Louis.
Ryan BogdanDepartment of Psychological & Brain Sciences, Washington University in St. Louis.
Arpana AgrawalDepartment of Psychiatry, Washington University School of Medicine.
Funding
ABCD-USA Consortium: Coordinating CenterU24DA041147 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SANDRA A BROWN, TERRY L. JERNIGAN · 2015 to 2026
$54.7MABCD-USA Consortium: Data Analysis, Informatics and Resource CenterU24DA041123 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ANDERS M DALE · 2015 to 2026
$51.5MAdolescent Substance Use Initiation: Disentangling neurocognitive risks from consequences using longitudinal and genetically-informed methodsU01DA041120 · NIDA · UNIVERSITY OF MINNESOTA · PI Monica Luciana, Sylia Wilson · 2015 to 2026
$34.5MABCD-USA Consortium: Research ProjectU01DA041089 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Joanna Jacobus, Susan F. Tapert · 2015 to 2026
$31.7MProspective Research Studies of Maturation (PRISM)- Research ProjectU01DA041134 · NIDA · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI ERIN MCGLADE, PERRY FRANKLIN RENSHAW · 2015 to 2026
$29.2MABCD-USA CONSORTIUM: RESEARCH PROJECTU01DA041048 · NIDA · CHILDREN'S HOSPITAL OF LOS ANGELES · PI Megan Marie Herting, ELIZABETH R SOWELL · 2015 to 2026
$28.7MABCD-USA Consortium: Research ProjectU01DA041106 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mary M Heitzeg, Chandra Sekhar Sripada · 2015 to 2026
$24.9MFIU-ABCD: Pathways and Mechanisms to Addiction in the Latino Youth of South FloridaU01DA041156 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI Raul Gonzalez, Angela R Laird · 2015 to 2026
$22.8MABCD-USA Consortium: Research ProjectU01DA041148 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI Damien A Fair, Rebekah S Huber · 2015 to 2026
$22.3MABCD-USA: NYC Research ProjectU01DA041174 · NIDA · YALE UNIVERSITY · PI Arielle Ryan Baskin-Sommers, Betty J Casey · 2015 to 2026
$19.7MAdolescent Brain Cognitive Development (ABCD) Prospective Research in Studies of Maturation (PRISM) ConsortiumU01DA041117 · NIDA · UNIVERSITY OF MARYLAND BALTIMORE · PI LINDA CHANG, THOMAS M ERNST · 2015 to 2026
$19.5MABCD-USA Consortium:Research ProjectU01DA041028 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DUNCAN B. CLARK, BEATRIZ LUNA · 2015 to 2026
$13.9MNIAAA NIH HHS K01 AA031724NIDA NIH HHS K01 DA051759NIDA NIH HHS R01 DA054750NIDA NIH HHS T32 DA007261NIDA NIH HHS U01 DA041022NIDA NIH HHS U01 DA041025NIDA NIH HHS U01 DA041028NIDA NIH HHS U01 DA041048NIDA NIH HHS U01 DA041089NIDA NIH HHS U01 DA041093NIDA NIH HHS U01 DA041106NIDA NIH HHS U01 DA041117NIDA NIH HHS U01 DA041120NIDA NIH HHS U01 DA041134NIDA NIH HHS U01 DA041148NIDA NIH HHS U01 DA041156NIDA NIH HHS U01 DA041174NIDA NIH HHS U24 DA041123NIDA NIH HHS U24 DA041147NIMH NIH HHS R01 MH139880
6 · The paper itselfAbstract
The Big 5 personality traits (extraversion, agreeableness, conscientiousness, neuroticism, openness to experience) are moderately heritable correlates of behavior, health, and life outcomes. Characterizing childhood expressions of genetic variation associated with adult personality may inform our understanding of personality development and how personality becomes associated with behaviors and environments. Our phenome-wide association study (PheWAS) of Big 5 polygenic indices (PGIs) among children (n
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PMID42818867
PMCPMC13622791
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