Evidence map›Paper›PMID 42818857›Full record

ArticlemedRxiv : the preprint server for health sciences2026

Relationship between mental health and unmet need for contraception and method type among women living with HIV in Kenya.

Agnes Karingo Karume, Aparna Seth, Nancy Ngumbau, Celestine Atieno, June Moraa, Kristin Beima-Sofie, Barbra A Richardson, Jennifer A Unger, Amritha Bhat, John Kinuthia and 1 more

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

11 authors.

Agnes Karingo KarumeDepartment of Research & Programs, Kenyatta National Hospital.ORCID 0000-0002-3425-2391
Aparna SethDepartment of Global Health, University of Washington.
Nancy NgumbauDepartment of Research & Programs, Kenyatta National Hospital.ORCID 0000-0003-4176-5950
Celestine AtienoDepartment of Research & Programs, Kenyatta National Hospital.
June MoraaDepartment of Research & Programs, Kenyatta National Hospital.
Kristin Beima-SofieDepartment of Global Health, University of Washington.
Barbra A RichardsonDepartment of Global Health, University of Washington.
Jennifer A UngerDepartment of Obstetrics and Gynaecology, Warren Alpert Medical School of Brown University, Women and Infants Hospital.
Amritha BhatDepartment of Psychiatry and Behavioural Sciences, University of Washington.
John KinuthiaDepartment of Research & Programs, Kenyatta National Hospital.
Alison L DrakeDepartment of Global Health, University of Washington.

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI EDWIN ROBERTO ORELLANA · 1988 to 2026
$104.9M
Promoting Diversity, Equity, and Inclusivity in Research Training to Optimize HIV Prevention and TreatmentD43TW009580 · FIC · UNIVERSITY OF WASHINGTON · PI CAREY FARQUHAR, John Kinuthia · 2013 to 2026
$4.8M
Mobile WACh Empower: Mobile solutions to empower reproductive life planning for women living with HIVR01HD104551 · NICHD · UNIVERSITY OF WASHINGTON · PI DRAKE, ALISON L · 2021 to 2025
$3.5M
FIC NIH HHS D43 TW009580NIAID NIH HHS P30 AI027757NICHD NIH HHS R01 HD104551
6 · The paper itself

Abstract

Contraception is important for preventing unintended pregnancies and reducing maternal and infant mortality. Among women living with HIV (WLHIV), it is also central to preventing vertical HIV transmission. Yet unmet need for contraception remains high among WLHIV in sub-Saharan Africa. Mental health symptoms may contribute to unmet need, but evidence among WLHIV remains limited. We examined the relationship between depression and anxiety and unmet need for contraception. We used baseline survey data from Kenyan WLHIV receiving routine HIV care participating in a cluster randomized clinical trial evaluating a reproductive health counselling intervention at 10 HIV clinics. Women who were fecund, did not desire a pregnancy within two years, and not using a modern method of contraception were considered to have unmet need for contraception and were eligible for this analysis. Surveys captured data on depression, anxiety, fertility intentions and contraceptive use. We constructed separate generalized linear models to assess the relationship between depression and/or anxiety and unmet need for contraception. Among 2,334 women in the analysis, the median age was 34; 9% (n=221) reported symptoms of at least mild depression, 9% (n=200) anxiety, 13% (n=305) either condition, and 5% (n=116) both. Overall, 84% (n=1,952) used a modern contraceptive method, 16% (n=378) had an unmet need for contraception, and 41% (n=784) used LARC. In univariate analysis, unmet need for contraception was 43% higher among women with either at least mild depression or at least mild anxiety (Prevalence Ratio [PR]=1.43, 95% Confidence Interval [CI]: 1.22-1.67); results were similar in the adjusted model (adjusted PR [aPR]=1.30, 95% CI: 1.08-1.58). No relationships were detected between anxiety or depression alone and unmet need. WLHIV with either depression or anxiety had higher unmet need which suggests that mental health conditions may pose barriers to contraceptive use and may need additional support to achieve their reproductive health goals. Additional attention to mental health needs during contraceptive counselling may support informed contraceptive decision-making.

Indexed as

AnxietyContraceptionDepressionFamily planningUnmet need for contraceptionWomen living with HIV

Identifiers

PMID42818857
PMCPMC13622795

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.