SynthesisFrontiers in surgery2026
Joint fibrosis research from a multi-joint perspective: a bibliometric analysis, 2000-2025.
Synthesis in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Joint fibrosis is a pathological process characterized by abnormal tissue repair, excessive extracellular matrix deposition, and fibrous adhesions. It can affect multiple joints and cause pain, restricted motion, and functional impairment. Existing research has largely focused on specific joints or surgical procedures, and the overall research landscape and literature distribution across joints have not been systematically characterized. Methods: Scopus and the Web of Science Core Collection were searched using a strategy that combined a fibrosis-specific concept module with a joint anatomy module. After restriction, merging, and deduplication, 1,600 English-language articles and reviews were included. Bibliometric analyses were performed in R using bibliometrix, Biblioshiny, and ggplot2. Results: Publication output on joint fibrosis increased overall from 2000 to 2025, with an annual growth rate of 9.81%; annual publications rose from 19 in 2000 to 197 in 2025. Author keywords centered on arthrofibrosis and were closely associated with total knee arthroplasty, anterior cruciate ligament reconstruction, joint stiffness, postoperative complications, and functional recovery. Anatomical classification identified 1,143 knee-related publications, substantially more than for any other joint. Collaboration networks comprised several relatively concentrated author and institutional groups, while the United States occupied a central position in publication output, international collaboration, and the country collaboration network. Conclusion: Within the available bibliographic data, joint fibrosis research was highly concentrated on the knee and focused primarily on joint arthroplasty, ligament reconstruction, and postoperative functional management. Future research should adopt standardized definitions and outcome measures, expand investigation to underrepresented joints, and integrate mechanistic and prospective clinical studies to improve the diagnosis, prevention, and management of joint fibrosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.