Evidence map›Paper›PMID 42818300›Full record

ArticlebioRxiv : the preprint server for biology2026

TFAM Dependent Mitochondrial Fitness Limits CD8

Zahrasadat Navaeiseddighi, Kai Guo, Syed Shafat Hasan, Zhihan Wang, Rutuparnna Mishra, Taylor Schmit, Jamanah Ahsan, Emily J Moser, Junguk Hur, Jacob S Yount and 3 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zahrasadat NavaeiseddighiDept of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL, USA.
Kai GuoDepartment of Neurology, University of Michigan, Ann Arbor, MI 48109, USA.
Syed Shafat HasanDept of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL, USA.
Zhihan WangDepartment of Human Anatomy, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, 610500, China.
Rutuparnna MishraDept of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL, USA.
Taylor SchmitDept of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL, USA.
Jamanah AhsanDept of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL, USA.
Emily J MoserDivision of Pulmonary, Critical Care & Sleep Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.
Junguk HurDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND 58202, USA.
Jacob S YountDepartment of Microbial Infection & Immunity, The Ohio State University. Columbus, OH 43210.
Ramkumar MathurDept. of Geriatrics, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND 58202, USA.
Liang ZhouDepartment of Infectious Diseases and Immunology, Center for Inflammation and Mucosal Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL, 32608 USA.
Nadeem KhanDept of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL, USA.

Funding

Role of RORgt+ (note: g: is gamma symbol) lymphocytes in Gut Tissue HomeostasisR01AI157109 · NIAID · UNIVERSITY OF FLORIDA · PI ZHOU, LIANG · 2021 to 2025
$2.8M
Pathogenic role of IL-17 response in Streptococcus pneumoniae nasopharyngeal pathogenesis during an influenza virus co-infectionR01AI143741 · NIAID · UNIVERSITY OF NORTH DAKOTA · PI KHAN, NADEEM · 2020 to 2024
$1.9M
Utilization of the adjuvant effect of CRM197 protein to develop a trivalentprotein-vaccine against Streptococcus pneumoniae infectionsR21AI151522 · NIAID · UNIVERSITY OF NORTH DAKOTA · PI KHAN, NADEEM · 2021 to 2022
$402k
NIAID NIH HHS R01 AI143741NIAID NIH HHS R01 AI157109NIAID NIH HHS R21 AI151522
6 · The paper itself

Abstract

During respiratory virus infection, CD8

Indexed as

CD8+ T cellsInfluenza A virus infectionMitochondrial dysfunctionMitochondrial transcription factor A (TFAM)

Identifiers

PMID42818300
PMCPMC13622243

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.