Evidence map›Paper›PMID 42818281›Full record

ArticlebioRxiv : the preprint server for biology2026

Genome-wide fitness profiling reveals flagellar rotation as an energetic liability during anaerobic maintenance in

Kemal Demirer, Ryan A Melnyk, Hans K Carlson, Akihiro Okamoto, Adam M Deutschbauer, Dianne K Newman

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kemal DemirerDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, USA.
Ryan A MelnykEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA.
Hans K CarlsonEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA.ORCID 0000-0002-1583-5313
Akihiro OkamotoResearch Center for Macromolecules and Biomaterials, National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki, 305-0044, Japan.ORCID 0000-0002-8102-4316
Adam M DeutschbauerEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA.
Dianne K NewmanDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, USA.ORCID 0000-0003-1647-1918

Funding

Leveraging phenazine cycling to understand maintenance metabolism in Pseudomonas aeruginosaR01AI189726 · NIAID · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI Dianne K Newman · 2026 to 2026
$711k
NIAID NIH HHS R01 AI189726
6 · The paper itself

Abstract

Bacteria in nature and disease frequently spend time in non-growing states, yet the genes that allow cells to survive without growing remain poorly understood. Using

Indexed as

energy limitationflagellagrowth arrestphenazinePseudomonas aeruginosatransposon sequencing

Identifiers

PMID42818281
PMCPMC13622516

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.