ArticlebioRxiv : the preprint server for biology2026
KMT2E recruitment by H3 serotonylation regulates neurodevelopmental chromatin dynamics.
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In one paragraph
Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
27 authors.
Jennifer C O'ChanNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Benjamin H WeekleyNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Celi YangDepartment of Basic Medical Sciences, School of Medicine at Tsinghua University, Beijing, China.
Min ChenNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Ashley M CunninghamNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Sohini DuttaNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Winnie ChenNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Rasika R IyerNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Newaz I AhmedNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Bulent CetinNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Cari A SagumDepartment of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Bradley J LukasakDepartment of Chemistry, Princeton University, Princeton, New Jersey 08544, USA.
Erdene BaljinnyamDepartment of Stem Cell Biology and Regenerative Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Zoé Christenson WickNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.ORCID 0000-0002-2752-0140
Vishwendra PatelNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Emma AndrakaNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Aarthi RamakrishnanNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Christopher PeraltaThe Rockefeller University Proteomics Resource Center, The Rockefeller University, New York, NY 10065, USA.
Li ShenNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.ORCID 0000-0002-5190-2851
Henrik MolinaThe Rockefeller University Proteomics Resource Center, The Rockefeller University, New York, NY 10065, USA.
Tristan ShumanNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.ORCID 0000-0003-2310-6142
Robert D BlitzerNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Tom W MuirDepartment of Chemistry, Princeton University, Princeton, New Jersey 08544, USA.
Mark T BedfordDepartment of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Samuele G MarroThe Rockefeller University Proteomics Resource Center, The Rockefeller University, New York, NY 10065, USA.ORCID 0000-0002-9326-6945
Haitao LiDepartment of Basic Medical Sciences, School of Medicine at Tsinghua University, Beijing, China.ORCID 0000-0001-6741-293X
Ian MazeNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Funding
TRAINING IN PHARMACOLOGY OF DRUGS OF ABUSET32DA007135 · NIDA · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI DEVI, LAKSHMI A · 1985 to 2018
$4.9MMolecular studies of neural histone monoaminylation in normal and aberrant brain plasticityR01MH116900 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Ian S. Maze · 2019 to 2026
$4.7MProjection-specific mechanisms mediating postpartum stress effects on the maternal brainK01MH139990 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Jennifer C Chan · 2026 to 2026
$718kRole of POU4F1 in a Novel Form of AtaxiaR21NS130319 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI MARRO, SAMUELE G., WEBB, BRYN D · 2023 to 2024
$464kImpact of histone serotonylation domain organization on neurodevelopmentF32MH126534 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CHAN, JENNIFER C · 2021 to 2023
$216kInvestigating Histone 3 Dopaminylation in Parkinson's DiseaseF30AG090096 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Winnie Chen · 2024 to 2026
$152kMechanisms of Histone Serotonylation and MLL5 in Coordinating the Epigenome during NeurodevelopmentF32MH140478 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Benjamin H Weekley · 2025 to 2026
$152kFunctional Role for H3 Serotonylation During Critical Periods of Postnatal Brain Development and PlasticityF31NS132558 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CUNNINGHAM, ASHLEY · 2023 to 2024
$70kCell-type Specific Roles for H3 Serotonylation During Critical Periods of Postnatal Brain Development and PlasticityF99NS139541 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CUNNINGHAM, ASHLEY · 2024 to 2024
$49kNIA NIH HHS F30 AG090096NIDA NIH HHS T32 DA007135NIMH NIH HHS F32 MH126534NIMH NIH HHS F32 MH140478NIMH NIH HHS K01 MH139990NIMH NIH HHS R01 MH116900NINDS NIH HHS F31 NS132558NINDS NIH HHS F99 NS139541NINDS NIH HHS R21 NS130319
Abstract
Histone H3 Gln 5 serotonylation (H3Q5ser) is a recently identified epigenetic modification in brain that modulates
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.