Evidence map›Paper›PMID 42818162›Full record

ArticlebioRxiv : the preprint server for biology2026

Exploring roles for essential proteins in yeast filamentous growth identifies the WASP homolog Las17 as a regulator of the Cdc42-dependent fMAPK pathway.

Atindra N Pujari, Ankita Priyadarshini, Zhijian Li, Ankita S Darekar, Deanna Williams, Dale Climie, Sondra Bahr, Helena Friesen, Michelle Li, Joshua M Oken and 4 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Atindra N PujariDepartment of Biological Sciences, University at Buffalo, Buffalo, New York 14260.
Ankita PriyadarshiniDepartment of Biological Sciences, University at Buffalo, Buffalo, New York 14260.
Zhijian LiTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON M5S 3E1, Canada.
Ankita S DarekarDepartment of Biological Sciences, University at Buffalo, Buffalo, New York 14260.
Deanna WilliamsDepartment of Biological Sciences, University at Buffalo, Buffalo, New York 14260.
Dale ClimieTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON M5S 3E1, Canada.
Sondra BahrTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON M5S 3E1, Canada.
Helena FriesenTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON M5S 3E1, Canada.
Michelle LiDepartment of Biological Sciences, University at Buffalo, Buffalo, New York 14260.
Joshua M OkenDepartment of Biological Sciences, University at Buffalo, Buffalo, New York 14260.
Robert M RomitoIndependent Consultant, Amherst, New York.
Brenda AndrewsTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON M5S 3E1, Canada.
Charles BooneTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON M5S 3E1, Canada.
Paul J CullenDepartment of Biological Sciences, University at Buffalo, Buffalo, New York 14260.ORCID 0000-0002-6703-1480

Funding

Control of MAPK Signaling by Cell Polarity ProteinsR01GM098629 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CULLEN, PAUL JAMES · 2011 to 2024
$4.4M
NIGMS NIH HHS R01 GM098629
6 · The paper itself

Abstract

Cell differentiation into distinct cell types generates functional specialization in eukaryotic organisms. Many fungal species undergo filamentous growth, where cells differentiate into elongated and adhesive filaments capable of expansion and invasion into new environments. The budding yeast

Indexed as

biofilm/mat formationcell differentiationfilamentous growthfunctional genomicsinvasive growthMAPK pathwaysprotein traffickingresource

Identifiers

PMID42818162
PMCPMC13622123

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.