Evidence map›Paper›PMID 42818138›Full record

ArticlebioRxiv : the preprint server for biology2026

Emergence of short-lived meningococci causing focal epidemics can be associated with gene transfer from carriage-associated

Charlene Mc Rodrigues, Jay Lucidarme, Rachel Exley, Jack Llewellyn Clark, Xilian Bai, Chris Bayliss, Meera Chand, Stephen A Clark, Cynthia Nau Cornelissen, Jeremy P Derrick and 13 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Charlene Mc RodriguesUK Health Security Agency, London, United Kingdom.ORCID 0000-0003-0942-3707
Jay LucidarmeMeningococcal Reference Unit, UK Health Security Agency, United Kingdom.ORCID 0000-0001-5553-2512
Rachel ExleySir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Jack Llewellyn ClarkDivision of Microbiology and Infection, School of Biological and Biomedical Sciences, University of Leicester, United Kingdom.ORCID 0009-0006-8315-0398
Xilian BaiMeningococcal Reference Unit, UK Health Security Agency, United Kingdom.
Chris BaylissDivision of Microbiology and Infection, School of Biological and Biomedical Sciences, University of Leicester, United Kingdom.
Meera ChandUK Health Security Agency, London, United Kingdom.ORCID 0000-0001-9697-0340
Stephen A ClarkMeningococcal Reference Unit, UK Health Security Agency, United Kingdom.
Cynthia Nau CornelissenInstitute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, United States.ORCID 0000-0001-6294-6588
Jeremy P DerrickSchool of Biological Sciences, Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester, United Kingdom.ORCID 0000-0002-4350-5354
Luke R GreenFlorey Institute of Infection, School of Clinical Dentistry, University of Sheffield, United Kingdom.ORCID 0000-0002-2836-2041
Natalie GrovesUK Health Security Agency, London, United Kingdom.ORCID 0000-0002-3832-3484
Yaiza Gutierrez VazquezMeningococcal Reference Unit, UK Health Security Agency, United Kingdom.ORCID 0009-0009-5930-1928
Odile B HarrisonNuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-1623-0295
Keith A JolleyDepartment of Biology, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-0751-0287
Samantha A McKeandSir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.ORCID 0000-0001-5579-7422
Richard MyersUK Health Security Agency, London, United Kingdom.
Nicholas NoinajDepartment of Biological Sciences, Markey Center for Structural Biology, and the Purdue Institute of Inflammation, Immunology and Infectious Disease, Purdue University, West Lafayette, Indiana 47907, United States.ORCID 0000-0001-6361-2336
Kasia M ParfittDepartment of Biology, University of Oxford, Oxford, United Kingdom.ORCID 0000-0001-7511-1459
Paolo RibecaUK Health Security Agency, London, United Kingdom.ORCID 0000-0001-5599-3933
Ray BorrowMeningococcal Reference Unit, UK Health Security Agency, United Kingdom.ORCID 0000-0002-0691-6568
Martin Cj MaidenDepartment of Biology, University of Oxford, Oxford, United Kingdom.ORCID 0000-0001-6321-5138
Christoph M TangSir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.ORCID 0000-0001-8366-3245

Funding

Neisseria gonorrhoeae metal transporters that subvert nutritional immunityR01AI127793 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI CYNTHIA N CORNELISSEN, Alison K Criss · 2017 to 2026
$6.8M
NIAID NIH HHS R01 AI127793Wellcome Trust
6 · The paper itself

Abstract

In March 2026, an unusually large outbreak of invasive meningococcal disease (IMD) in Kent, UK, was linked to attendance at one nightclub over a single weekend. The outbreak organism was a

Indexed as

Biological Sciencesfocal outbreakgenomicshorizontal gene transferMicrobiologyNeisseria meningitidis

Identifiers

PMID42818138
PMCPMC13622092

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.