ArticlebioRxiv : the preprint server for biology2026
Substrate Profiling of RNF216 Uncovers a Translation-Linked OTUD4 Regulatory Axis.
Wei Wei, Ruochuan Liu, Jing Zhang, Shu Liu, Antoinette J Charles, Devansh G Asati, Zachary D Allen, Delance Wright, Kangli Peng, Ellissa Krekeler and 3 more
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
13 authors.
Wei WeiNeuroscience Institute and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, USA.ORCID 0009-0004-2411-0930 Ruochuan LiuDepartment of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, USA.
Jing ZhangDepartment of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, USA.
Shu LiuDepartment of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, USA.ORCID 0000-0001-8000-8106 Antoinette J CharlesNeuroscience Institute and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, USA.
Devansh G AsatiNeuroscience Institute and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, USA.
Zachary D AllenNeuroscience Institute and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, USA.ORCID 0000-0003-2179-8798 Delance WrightNeuroscience Institute and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, USA.
Kangli PengDepartment of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, USA.
Ellissa KrekelerDepartment of Pathology & Immunology, Center for Genome Integrity, Washington University School of Medicine, St. Louis, MO 63110, USA.
Nima MosammaparastDepartment of Pathology & Immunology, Center for Genome Integrity, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0001-5453-5914 Jun YinDepartment of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, USA.ORCID 0000-0002-4803-7510 Angela M MabbNeuroscience Institute and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, USA.ORCID 0000-0002-3000-8690 Funding
Transcription-Coupled & Replication-Associated Excision RepairP01CA092584 · NCI · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI John A. Tainer · 2001 to 2026
$89.6MAn RNA-Dependent Innate Immune Response Pathway to Base-Damaging ChemotherapeuticsR01CA282733 · NCI · WASHINGTON UNIVERSITY · PI Nima Mosammaparast · 2024 to 2026
$1.5MRNA damage induced DNA breaks: A new mechanism of genome instabilityR01GM160854 · NIGMS · WASHINGTON UNIVERSITY · PI MOSAMMAPARAST, NIMA · 2025 to 2025
$855kProtein ubiquitination and deubiquitination in neurological disordersR01NS136464 · NINDS · GEORGIA STATE UNIVERSITY · PI Angela M Mabb · 2025 to 2026
$811kZeiss LSM 980 with Airyscan 2 for Imaging Core FacilityS10OD032336 · OD · GEORGIA STATE UNIVERSITY · PI CHEN, KUANGCAI · 2022 to 2022
$597kInsights into Gordon Holmes syndrome by substrate profiling of Triad3A and Chip using Orthogonal Ubiquitin TransferR21NS116760 · NINDS · GEORGIA STATE UNIVERSITY · PI MABB, ANGELA M, YIN, JUN · 2021 to 2021
$429kNCI NIH HHS P01 CA092584NCI NIH HHS R01 CA282733NIGMS NIH HHS R01 GM160854NIH HHS S10 OD032336NINDS NIH HHS R01 NS136464NINDS NIH HHS R21 NS116760
6 · The paper itselfAbstract
Mutations in the E3 Ubiquitin (Ub) ligase
Indexed as
Gordon Holmes syndromeneuronOTUD4protein synthesisRNF216ubiquitin
Identifiers
PMID42817983
PMCPMC13621970
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