Evidence map›Paper›PMID 42817959›Full record

ArticlebioRxiv : the preprint server for biology2026

Fluorescent proteins misreport ribosome abundance under translation inhibition.

Aniket Zodage, Justin Chen, Nabigha Mogharbel, Hidde de Jong, Suckjoon Jun

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aniket ZodagePhysics Department, University of California San Diego, La Jolla, CA.ORCID 0000-0001-5044-0731
Justin ChenDepartment of Chemical and NanoEngineering, University of California San Diego, La Jolla, CA.
Nabigha MogharbelUniversité Grenoble Alpes, Inria, Grenoble, France.
Hidde de JongUniversité Grenoble Alpes, Inria, Grenoble, France.ORCID 0000-0002-2226-650X
Suckjoon JunPhysics Department, University of California San Diego, La Jolla, CA.ORCID 0000-0002-0139-4297

Funding

Control of cellular resource allocation across biological scales in microorganismsR35GM139622 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JUN, SUCKJOON · 2021 to 2025
$2.3M
NIGMS NIH HHS R35 GM139622
6 · The paper itself

Abstract

Fluorescent proteins are widely used as quantitative reporters of protein abundance in living cells. Here we show that this relationship can break down under translation inhibition: the cellular ribosomal abundance can increase while fluorescence intensity remains unchanged or even decreases. Using fluorescent reporters of ribosome abundance in

Identifiers

PMID42817959
PMCPMC13622061

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.