Evidence map›Paper›PMID 42817875›Full record

ReviewArteriosclerosis, thrombosis, and vascular biology2026

PET Imaging in Pulmonary Hypertension.

Mandy M T van Leent, Trea St Hillaire, Sanjay Sivalokanathan, Hidetaka Morita, Philip M Robson, Kiyotake Ishikawa, Maria Giovanna Trivieri

Abstract readReview
In one paragraph

Review in Arteriosclerosis, thrombosis, and vascular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mandy M T van LeentBioMedical Engineering and Imaging Institute (M.M.T.v.L., T.S.H., P.M.R., M.G.T.), Icahn School of Medicine at Mount Sinai, New York, NY.ORCID 0000-0002-9747-1022
Trea St HillaireBioMedical Engineering and Imaging Institute (M.M.T.v.L., T.S.H., P.M.R., M.G.T.), Icahn School of Medicine at Mount Sinai, New York, NY.
Sanjay SivalokanathanMount Sinai Fuster Heart Hospital (S.S., M.G.T.), Icahn School of Medicine at Mount Sinai, New York, NY.ORCID 0000-0002-3227-3295
Hidetaka MoritaCardiovascular Research Institute (M.M.T.v.L., T.S.H., H.M., K.I., M.G.T.), Icahn School of Medicine at Mount Sinai, New York, NY.
Philip M RobsonBioMedical Engineering and Imaging Institute (M.M.T.v.L., T.S.H., P.M.R., M.G.T.), Icahn School of Medicine at Mount Sinai, New York, NY.ORCID 0000-0002-4916-970X
Kiyotake IshikawaCardiovascular Research Institute (M.M.T.v.L., T.S.H., H.M., K.I., M.G.T.), Icahn School of Medicine at Mount Sinai, New York, NY.ORCID 0000-0002-8287-3483
Maria Giovanna TrivieriBioMedical Engineering and Imaging Institute (M.M.T.v.L., T.S.H., P.M.R., M.G.T.), Icahn School of Medicine at Mount Sinai, New York, NY.ORCID 0000-0001-6601-3267

Funding

Translational imaging and nanomedicine in inflammatory atherosclerosisP01HL131478 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Zahi A. Fayad · 2017 to 2026
$24.3M
Preclinical imaging of immune responses to chronic stressR01HL169500 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Mandy Maria Theresia van Leent · 2023 to 2026
$2.5M
NHLBI NIH HHS P01 HL131478NHLBI NIH HHS R01 HL169500
6 · The paper itself

Abstract

Pulmonary hypertension comprises a heterogeneous group of diseases characterized by elevated pulmonary arterial pressures and progressive right ventricular (RV) remodeling, with RV failure as the principal determinant of outcome. This review discusses positron emission tomography (PET) imaging across pulmonary hypertension, with particular emphasis on pulmonary arterial hypertension, in which pulmonary vascular remodeling and RV adaptation are central disease features. Although echocardiography and cardiac magnetic resonance imaging provide robust assessment of RV structure, function, and fibrosis, they are limited in detecting early molecular alterations that precede overt dysfunction. PET offers a unique opportunity to visualize these processes. In particular, [

Indexed as

fibrosishypertensionhypertrophyinflammationpulmonarytherapeutics

Identifiers

PMID42817875
PMCPMC13632654

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.