Evidence map›Paper›PMID 42817585›Full record

ArticleCancer medicine2026

Self-Reported Cancer-Related Cognitive Impairment and Psychosocial Symptom Burden in Survivors of Head and Neck Cancer.

Matthew E Lin, Jake Stenzel, Desiree Delavary, Maie A St John, Deborah J Wong, Patricia A Ganz, Eden R Brauer

Abstract read
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In one paragraph

Article in Cancer medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Matthew E LinDepartment of Head and Neck Surgery, David Geffen School of Medicine at University of California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0001-9914-9670
Jake StenzelDepartment of Head and Neck Surgery, David Geffen School of Medicine at University of California, Los Angeles, California, USA.
Desiree DelavaryA.T. Still University School of Osteopathic Medicine, Mesa, Arizona, USA.ORCID https://orcid.org/0000-0001-9259-6363
Maie A St JohnDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medicine, Baltimore, Maryland, USA.
Deborah J WongMultidisciplinary Head and Neck Cancer Program, UCLA Health, Los Angeles, California, USA.
Patricia A GanzDepartment of Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles (UCLA), Los Angeles, California, USA.ORCID https://orcid.org/0000-0002-1841-4143
Eden R BrauerMultidisciplinary Head and Neck Cancer Program, UCLA Health, Los Angeles, California, USA.ORCID https://orcid.org/0000-0003-4895-1748

Funding

Harnessing the EHR for the Delivery of Supportive Care in an Oncology SettingK08CA252615 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BRAUER, EDEN R. · 2021 to 2025
$934k
Jonsson Comprehensive Cancer CenterNCI NIH HHS K08 CA252615NCI NIH HHS K08CA252615
6 · The paper itself

Abstract

backgroundCancer-related cognitive impairment (CRCI) is an increasingly recognized survivorship concern, yet its prevalence and associated clinical and psychosocial factors among survivors of head and neck cancer (HNC) remain poorly characterized.

methodsThis cross-sectional study recruited survivors of HNC, who were at least 1-year post-diagnosis, from an institutional tumor registry to complete a comprehensive survey. Self-reported cognitive function was assessed using the PROMIS Cognitive Function Short Form 8a, with a T-score < 40 indicating cognitive impairment. Symptom burden was assessed using the EORTC QLQ-HN43, PROMIS short forms, and the Insomnia Severity Index. Social role functioning was assessed using the PROMIS Satisfaction with Participation in Social Roles short form. Multivariable linear and logistic regression examined factors independently associated with self-reported cognitive impairment.

resultsOf 337 survey respondents, 41 survivors (12.2%) met criteria for self-reported moderate to severe cognitive impairment. Cognitively impaired survivors reported significantly higher symptom burden and lower social role functioning than survivors within normal limits. In multivariable linear regression (R

conclusionsApproximately one in eight HNC survivors reported moderate-to-severe cognitive impairment. Self-reported cognitive difficulty was associated with psychosocial symptom burden and multimodal treatment, and co-occurred with poorer social role functioning. These findings support concurrent assessment of cognitive and psychosocial symptoms in HNC survivorship care.

Indexed as

Cancer SurvivorsCognitive DysfunctionHead and Neck NeoplasmsAdultAgedCross-Sectional StudiesFatigueFemaleHumansMaleMiddle AgedQuality of LifeSelf ReportSymptom Burdencancer‐related cognitive impairmenthead and neck cancerpatient‐reported outcomespsychosocial symptomssurvivorship

Identifiers

PMID42817585
PMCPMC13628158

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.