Evidence map›Paper›PMID 42817163›Full record

ReviewJournal of mass spectrometry : JMS2026

Action Spectroscopy of Mass-Selected Ions-From Principles to Applications.

Pedro Henrique Martins Garcia, Gustavo Cervi, Cesar Augusto Gonçalves Dantas, Guilherme Obeid, Thiago C Correra

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of mass spectrometry : JMS, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pedro Henrique Martins GarciaDepartment of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, São Paulo, São Paulo, Brazil.
Gustavo CerviDepartment of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, São Paulo, São Paulo, Brazil.
Cesar Augusto Gonçalves DantasDepartment of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, São Paulo, São Paulo, Brazil.
Guilherme ObeidDepartment of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-8672-3028
Thiago C CorreraDepartment of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-8422-8701

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 306701/2023-5Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.512998/2020-00Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Finance code 001, Program 33002010191P0Fundação de Amparo à Pesquisa do Estado de São Paulo 2015/08539-1Fundação de Amparo à Pesquisa do Estado de São Paulo 2020/08894-4Fundação de Amparo à Pesquisa do Estado de São Paulo 2021/06726-0Fundação de Amparo à Pesquisa do Estado de São Paulo 2022/00498-8Fundação de Amparo à Pesquisa do Estado de São Paulo 2023/03008-4Fundação de Amparo à Pesquisa do Estado de São Paulo 2023/16303-4Fundação de Amparo à Pesquisa do Estado de São Paulo 2025/06785-7
6 · The paper itself

Abstract

Gas-phase ion spectroscopy provides direct, structure-sensitive information that complements and extends conventional mass spectrometry workflows, offering structural resolution that accurate mass and fragmentation patterns alone cannot always achieve by themselves. This review offers a practical entry point into the field by showcasing its analytical capabilities, addressed to mass spectrometrists and researchers from adjacent disciplines for whom ion spectroscopy represents an underexplored analytical resource. Four representative techniques are discussed: Electronic UV/Vis photodissociation (UVPD), infrared multiple photon dissociation spectroscopy (IRMPD), vibrational tagging photodissociation ion spectroscopy (IRPD), and helium nanodroplet isolation infrared spectroscopy (HENDI-IR). For each, the underlying physical principles are briefly introduced, and representative applications are presented with emphasis on problems of direct analytical relevance, including the structural characterization of isomeric metabolites, reactive intermediates, glycoconjugates, and drug-related compounds. Applications integrating ion spectroscopy with liquid chromatography (LC) and ion mobility spectrometry (IMS) are also discussed. The goal of this review is to convey, through carefully chosen examples, the breadth of problems that gas-phase ion spectroscopy is uniquely positioned to solve and to lower the threshold for its adoption by a wider scientific community.

Identifiers

PMID42817163
PMCPMC13627853

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.