Evidence map›Paper›PMID 42817048›Full record

Trial reportBrain and behavior2026

Application of an Exploratory DBT-Based Psychotherapy Program for Suicide-Related Symptoms in Chinese Outpatients With Affective Disorders.

Chanchan Hu, Jingkai Chen, Zhong Wang, Xiaoyi Zhou, Yujin Yang, Shuguang Li, Ruili Zhang, Jianbo Lai, Jianbo Hu, Manli Huang and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Brain and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chanchan HuThe First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jingkai ChenThe First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhong WangThe First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xiaoyi ZhouThe First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yujin YangOberlin College and Conservatory, Oberlin, Ohio, USA.
Shuguang LiThe First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Ruili ZhangThe First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jianbo LaiThe First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jianbo HuThe First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Manli HuangThe First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Shaohua HuThe First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Funding

Natural Science Foundation of Zhejiang Province LGC22H090001
6 · The paper itself

Abstract

objectiveThis exploratory pilot study aimed to examine the potential effects of a shortened, individually delivered dialectical behavior therapy (DBT)-based intervention added to pharmacotherapy on suicide-related outcomes among Chinese outpatients with affective disorders.

methodsTwenty-one participants recruited from the psychiatric outpatient clinics of the First Affiliated Hospital, School of Medicine, Zhejiang University, were randomly assigned to two groups. Participants in the research group received pharmacotherapy plus a shortened, individually delivered DBT-based intervention, whereas those in the control group received pharmacotherapy alone. Participants completed baseline assessments, 12 weeks of treatment, and 12 weeks of follow-up, with assessments performed every 4 weeks. Outcomes included suicide risk or severity, depression, anxiety, and hopelessness assessed using self-report scales.

resultsAfter adjustment for baseline values using repeated-measures analysis of covariance (RM-ANCOVA), the between-group effect on suicide risk showed a marginal trend favoring the DBT-based psychotherapy group, but did not reach conventional statistical significance (F = 4.26, p = 0.054). The time effect (F = 0.234, p = 0.965) and time-by-group interaction (F = 1.306, p = 0.261) for suicide risk were not statistically significant. Depressive symptoms showed a significant time effect across the follow-up period, whereas most suicide-related and hopelessness outcomes were not statistically significant. These findings should be interpreted as preliminary because of the small sample size and baseline imbalance.

conclusionThe results provided preliminary pilot evidence that a shortened DBT-based intervention may be feasible and potentially beneficial as an adjunct to pharmacotherapy in this clinical population. However, the primary suicide-risk outcome did not show a statistically significant between-group effect. Larger adequately powered trials with baseline-adjusted analyses and more comprehensive outcome assessment are needed before firm conclusions can be drawn.

Indexed as

Dialectical Behavior TherapyMood DisordersSuicide PreventionAdultAnxietyChinaCombined Modality TherapyDepressionEast Asian PeopleFemaleHumansMaleMiddle AgedOutpatientsPilot ProjectsSuicidal Ideationaffective disordersDBTpsychotherapysuicide

Identifiers

PMID42817048
PMCPMC13627894

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.