Evidence map›Paper›PMID 42816956›Full record

ArticleReproduction in domestic animals = Zuchthygiene2026

Small and Large Seminal Extracellular Vesicles Differentially Modulate Capacitation-Related Parameters in Frozen-Thawed Porcine Epididymal Spermatozoa.

Patricia Panales, Junwei Li, Ana Parra, Pablo Martínez-Díaz, Xiomara Lucas, Marc Yeste, Jordi Roca, Isabel Barranco

Abstract read
In one paragraph

Article in Reproduction in domestic animals = Zuchthygiene, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Patricia PanalesDepartment of Medicine and Animal Surgery, Faculty of Veterinary Science, University of Murcia, Murcia, Spain.
Junwei LiDepartment of Medicine and Animal Surgery, Faculty of Veterinary Science, University of Murcia, Murcia, Spain.
Ana ParraDepartment of Medicine and Animal Surgery, Faculty of Veterinary Science, University of Murcia, Murcia, Spain.
Pablo Martínez-DíazDepartment of Medicine and Animal Surgery, Faculty of Veterinary Science, University of Murcia, Murcia, Spain.
Xiomara LucasDepartment of Medicine and Animal Surgery, Faculty of Veterinary Science, University of Murcia, Murcia, Spain.ORCID https://orcid.org/0000-0002-7414-3149
Marc YesteBiotechnology of Animal and Human Reproduction (TechnoSperm), Institute of Food and Agricultural Technology, University of Girona, Girona, Spain.ORCID https://orcid.org/0000-0002-2209-340X
Jordi RocaDepartment of Medicine and Animal Surgery, Faculty of Veterinary Science, University of Murcia, Murcia, Spain.
Isabel BarrancoDepartment of Medicine and Animal Surgery, Faculty of Veterinary Science, University of Murcia, Murcia, Spain.ORCID https://orcid.org/0000-0001-9873-814X

Funding

Fundación Séneca (FSRM/10.13039/100007801) 21935/PI/22Fundación Séneca (FSRM/10.13039/100007801) 22784/FPI/24Fundación Séneca (FSRM/10.13039/100007801) 23014/GERM/25Ministerio de Ciencia, Innovación y Universidades (MICIU/AEI/10.13039/501100011033) PID2022-137738NA-I00Ministerio de Ciencia, Innovación y Universidades (MICIU/AEI/10.13039/501100011033) PID2023-149853OB-I00Ministerio de Ciencia, Innovación y Universidades (MICIU/AEI/10.13039/501100011033) PID2024-159343OB-I00Ministerio de Ciencia, Innovación y Universidades (MICIU/AEI/10.13039/501100011033) RYC2021-034546-I
6 · The paper itself

Abstract

Seminal extracellular vesicles (sEVs) have been proposed as modulators of sperm function, but their exact role remains unclear. Most studies use ejaculated sperm for clarification. This approach has limitations; nevertheless, as ejaculated sperm have already been exposed to their own native sEVs, which hinders the assessment of their specific roles. This study aimed to evaluate the potential impact of small (S-) and large (L-) sEVs on capacitation-related parameters of epididymal porcine spermatozoa. Frozen-thawed epididymal sperm were incubated in a non-capacitating medium with or without S- or L-sEVs at 37°C under 5% CO

Indexed as

Extracellular VesiclesSeminal VesiclesSpermatozoaSperm CapacitationAcrosomeAnimalsCalciumCryopreservationEpididymisMaleMembrane LipidsPhosphorylationSemen PreservationSwineCalciumMembrane Lipidscapacitationepididymal spermatozoaextracellular vesiclespigseminal plasma

Identifiers

PMID42816956
PMCPMC13627751

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.