Evidence map›Paper›PMID 42816949›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

A Neutrophil Membrane-Encapsulated Pd/hCeO

Lili Huang, Jiahui Cheng, Huan Xu, Qiang Zhang, Xiao Zhang, Ye Liu, Yizhe Zhang, Wanbing Dai, Zhi Xiong, Linghuan Guo and 8 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Lili Huang *Department of Anesthesiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Pudong, Shanghai, China.ORCID https://orcid.org/0009-0005-7928-8725
Jiahui Cheng *Department of Radiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Pudong, Shanghai, China.
Huan Xu *Department of Anesthesiology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Yangpu, Shanghai, China.ORCID https://orcid.org/0000-0002-7068-4992
Qiang ZhangInstitute of Diagnostic and Interventional Radiology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Xuhui, Shanghai, China.ORCID https://orcid.org/0009-0008-8671-4659
Xiao ZhangDepartment of Anesthesiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.ORCID https://orcid.org/0009-0007-0959-9178
Ye LiuDepartment of Anesthesiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yizhe ZhangDepartment of Anesthesiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Pudong, Shanghai, China.ORCID https://orcid.org/0009-0000-4047-5877
Wanbing DaiDepartment of Anesthesiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Pudong, Shanghai, China.
Zhi XiongInstitute of Diagnostic and Interventional Radiology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Xuhui, Shanghai, China.
Linghuan GuoInstitute of Diagnostic and Interventional Radiology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Xuhui, Shanghai, China.
Lingling XuDepartment of Radiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Pudong, Shanghai, China.
Wen WangDepartment of Radiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Pudong, Shanghai, China.
Xin XuDepartment of Radiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Pudong, Shanghai, China.
Yan ZhouDepartment of Radiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Pudong, Shanghai, China.
Weifeng YuDepartment of Anesthesiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Pudong, Shanghai, China.
Bo LiKey Laboratory of Anesthesiology (Shanghai Jiao Tong University), Ministry of Education, Pudong, Shanghai, China.ORCID https://orcid.org/0000-0001-9476-3073
Diansan SuDepartment of Anesthesiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.ORCID https://orcid.org/0000-0001-9755-1025
Daxiang WenDepartment of Anesthesiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Pudong, Shanghai, China.

Funding

Fundamental Research Funds for the Central Universities 25X010202804Funding of First Affiliated Hospital of Zhejiang University, School of Medicine BQD-2419National Natural Science Foundation of China 81970995National Natural Science Foundation of China 82371223National Natural Science Foundation of China 82401402National Natural Science Foundation of China 82571349National Natural Science Foundation of China U21A20357Sanming Project of Medicine in Shenzhen SZSM202311003Shanghai Engineering Research Center of Peri-operative Organ Support and Function Preservation 20DZ2254200Shanghai Science and Technology Committee Project 24ZR1444600Special Fund Project for Scientific Research of Young Doctors of Anesthesia and Pain MT23-1
6 · The paper itself

Abstract

Perioperative neurocognitive disorders (PND) are a prevalent and disabling complication in elderly patients after anesthesia and surgery, imposing a growing clinical burden in aging societies. Despite its high incidence, effective therapies for PND remain unavailable. Surgery-induced neuroinflammation, characterized by excessive oxidative stress, microglial activation, and blood-brain barrier (BBB) disruption, plays a central role in the development of PND. Here, we develop a PCN biomimetic nanozyme platform based on homologous, highly adhesive neutrophil membrane-encapsulated Pd/hCeO

Indexed as

agingglucometabolic reprogrammingmicroglial activationPd/hCeO2 nanozymeperioperative neurocognitive disorder

Identifiers

PMID42816949
PMCPMC13627777

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.