Evidence map›Paper›PMID 42816927›Full record

ArticleReproduction in domestic animals = Zuchthygiene2026

Extracellular Vesicles From Heat- and Oxidative-Stressed Granulosa Cells Improve Redox Balance and Embryo Development in Bovine Oocytes.

Judith Diaz-Muñoz, Yulia N Cajas, Karina Cañón-Beltrán, Sonia Gago, Carlos Olegario Hidalgo, Manel López-Béjar, Dimitrios Rizos, Teresa Mogas

Abstract read
In one paragraph

Article in Reproduction in domestic animals = Zuchthygiene, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Judith Diaz-MuñozAutonomous University of Barcelona, Cerdanyola del Vallès, Spain.
Yulia N CajasNational Institute for Agriculture and Food Research and Technology, Madrid, Spain.
Karina Cañón-BeltránNational Institute for Agriculture and Food Research and Technology, Madrid, Spain.
Sonia GagoAutonomous University of Barcelona, Cerdanyola del Vallès, Spain.
Carlos Olegario HidalgoSERIDA, Gijón, Spain.
Manel López-BéjarAutonomous University of Barcelona, Cerdanyola del Vallès, Spain.
Dimitrios RizosNational Institute for Agriculture and Food Research and Technology, Madrid, Spain.ORCID https://orcid.org/0000-0001-6813-3940
Teresa MogasAutonomous University of Barcelona, Cerdanyola del Vallès, Spain.ORCID https://orcid.org/0000-0002-6733-1328

Funding

Agència de Gestió d'Ajuts Universitaris i de Recerca 2021SGR00900Ministerio de Ciencia e Innovación PID2020-116531RB-I00Ministerio de Ciencia e Innovación PID2023-149027OB-I00Ministerio de Ciencia e Innovación PRE2021-098675
6 · The paper itself

Abstract

In vitro culture (IVC) exposes oocytes to suboptimal conditions that may disrupt redox homeostasis and compromise developmental competence. Extracellular vesicles (EVs) mediate intercellular communication, and their cargo reflects the physiological state of donor cells. We hypothesized that EVs derived from heat-stressed (HS) or oxidative-stressed (OS) granulosa cells (GCs) differentially modulate oocyte redox status and embryo development. GCs were exposed to 42°C for 24 h or to 5 μM H

Indexed as

Embryonic DevelopmentExtracellular VesiclesGranulosa CellsOocytesOxidative StressAnimalsCattleFemaleGlutathioneHot TemperatureIn Vitro Oocyte Maturation TechniquesMitochondriaOxidation-ReductionReactive Oxygen SpeciesGlutathioneReactive Oxygen Species3D segmentationglutathionemitochondrial activityreactive oxygen species

Identifiers

PMID42816927
PMCPMC13627749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.