ArticleAnnals of surgical oncology2026
Baseline Differences in Patient-Reported Quality of Life Across Breast Cancer Surgical Pathways.
Article in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
8 authors.
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Abstract
backgroundAdvancements in breast cancer treatment have led to excellent survival outcomes, shifting focus toward patient-centered measures. Although patient-reported outcomes (PROs), particularly the BREAST-Q
methodsWe performed a prospective cohort study of women aged ≥ 18 years with newly diagnosed stage I-III disease undergoing surgery from 2017 to 2024. Participants completed preoperative BREAST-Q
resultsIn total, 561 patients completed preoperative surveys. Significant baseline differences in PROs were observed across groups. On univariate analysis, all PRO domains except physical chest well-being differed significantly by procedure type. Multivariable analysis demonstrated that lower preoperative breast satisfaction and sexual well-being scores were associated with lumpectomy with oncoplastic reduction mammoplasty, bilateral mastectomy with reconstruction, and UMR compared with lumpectomy. Lower physical chest wall well-being was associated with unilateral mastectomy, and lower psychosocial well-being was associated with UMR.
conclusionSignificant preoperative differences in PROs exist across procedures. Incorporating PRO measures into preoperative evaluation may improve shared decision-making and individualized patient care.
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