ArticleJournal of molecular histology2026
Stanozolol, an anabolic-androgenic steroid, modulates expression of receptors and disrupts uterine histoarchitecture in Mus musculus.
Article in Journal of molecular histology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Abuse of Anabolic-Androgenic Steroids (AAS) by professional and recreational athletes for endurance performance and physique is increasing globally, consequently resulting in secondary pathophysiological effects. The present investigation aims to determine the effect of one of the AAS, stanozolol (ST), on uterine physiology and histology. A total of 15 female mice were assigned to three experimental groups (n = 5). ST was dosed subcutaneously (low-dose, 0.5 mg/kg bwt; high-dose, 5.0 mg/kg bwt or 1% alcohol-baseline control) for 30 days, and treatment was withdrawn on the 31st day. In this study, we evaluated histomorphometry of the uterus, immunoexpression of the estrogen receptor α (ERα), the androgen receptor (AR), and the prolactin receptor (PRLR), after ST treatment. In addition, we measured serum levels of testosterone (T), estradiol (E
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