ArticleNature2026
Population-scale immune multiome atlas reveals regulatory disease mechanisms.
Abstract read
In one paragraph
Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
43 authors.
Masahiro KanaiProgram in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0001-5165-4408
Toni M DeloreyKlarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0001-6614-3803
Jarno HonkanenBlood Service Biobank, Finnish Red Cross Blood Service, Vantaa, Finland.
Rodosthenis S RodosthenousInstitute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.ORCID http://orcid.org/0000-0002-2312-5530
Julianna JuvilaBlood Service Biobank, Finnish Red Cross Blood Service, Vantaa, Finland.
Shane MurphyKlarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Isabella Teixeira-SoldanoKlarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Hee Seung HwangKlarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0009-0001-5530-9238
Juha KarjalainenProgram in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Jussi HalonenBlood Service Biobank, Finnish Red Cross Blood Service, Vantaa, Finland.
Georgia PanagiotaropoulouProgram in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0001-9516-6158
Yuanxiang ZhangProgram in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-0695-4409
Cristin McCabeKlarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Eric ChenKlarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Kosaku NankiCenter for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA, USA.
Toshimi YoshidaCenter for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0001-7080-6913
Kai LiuCenter for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0002-8014-2310
Marla GleanKlarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Nitya MehrotraKlarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0001-7514-3362
Emily P FinanKlarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0009-0002-4134-5438
Daniel ChafamoKlarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0009-0001-8877-5913
Yixiao ZhuKlarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Mikko ArvasResearch and Development, Finnish Red Cross Blood Service, Helsinki, Finland.ORCID http://orcid.org/0000-0002-6902-8488
Sanni RuotsalainenInstitute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.ORCID http://orcid.org/0000-0002-1631-4069
Zhili ZhengProgram in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0003-2102-221X
Yoshihiko TomofujiDepartment of Genome Informatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Daiki TokuyasuDepartment of Genome Informatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Shinichi NambaDepartment of Genome Informatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID http://orcid.org/0000-0002-7486-3146
Kyuto SoneharaDepartment of Genome Informatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID http://orcid.org/0000-0002-4536-1761
BioBank Japan Project
FinnGen
Yukinori OkadaDepartment of Genome Informatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID http://orcid.org/0000-0002-0311-8472
Mary Pat ReeveProgram in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Mitja KurkiProgram in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Caroline B M PorterKlarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Orr AshenbergKlarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Wei ZhouProgram in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0001-7719-0859
Kimmo PitkänenBlood Service Biobank, Finnish Red Cross Blood Service, Vantaa, Finland.
Jukka PartanenBlood Service Biobank, Finnish Red Cross Blood Service, Vantaa, Finland.ORCID http://orcid.org/0000-0001-6681-4734
Aarno PalotieProgram in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-2527-5874
Daniel B GrahamCenter for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0002-8403-8115
Mark J DalyProgram in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. mjdaly@broadinstitute.org.ORCID http://orcid.org/0000-0002-0949-8752
Ramnik J XavierCenter for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA, USA. xavier@molbio.mgh.harvard.edu.ORCID http://orcid.org/0000-0002-5630-5167
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most disease-associated genetic variants lie in non-coding regions
Identifiers
PMID
42816628What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.