Evidence map›Paper›PMID 42816488›Full record

ArticleNature communications2026

A transmembrane protein confers the Yr26/Yr24/YrCH42/YrG22-mediated stripe rust resistance in wheat.

Shengjie Liu, Keqing Mu, Shuqing Yang, Jianhui Wu, Mingjie Xiang, Xiangrui Cheng, Xiaoting Wang, Yibo Zhang, Ying Zhao, Jiangna Han and 19 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Shengjie Liu *State Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, PR China.ORCID 0009-0006-4869-7726
Keqing Mu *State Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, PR China.
Shuqing Yang *State Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, PR China.
Jianhui Wu *State Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, PR China.ORCID 0000-0001-8154-1199
Mingjie XiangState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, PR China.
Xiangrui ChengState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, PR China.
Xiaoting WangState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, PR China.
Yibo ZhangState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, PR China.
Ying ZhaoState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, PR China.
Jiangna HanState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, PR China.
Shuo HuangKey Laboratory of Plant Design, Chinese Academy of Sciences, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, PR China.
Haitao DongState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, PR China.
Jiwen ZhaoState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, PR China.
Fengping YuanState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, PR China.
Raghvendra SharmaAgriculture and Food, Commonwealth Scientific and Industrial Research Organisation, Canberra, ACT, Australia.ORCID 0000-0002-7612-6932
Michael NormanAgriculture and Food, Commonwealth Scientific and Industrial Research Organisation, Canberra, ACT, Australia.
Peidu ChenCollege of Agronomy of Nanjing Agricultural University/State Key Laboratory of Crop Genetics & Germplasm Enhancement and Application /JCIC-MCP, Nanjing, PR China.
Aizhong CaoCollege of Agronomy of Nanjing Agricultural University/State Key Laboratory of Crop Genetics & Germplasm Enhancement and Application /JCIC-MCP, Nanjing, PR China.
Weijun ZhengState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, PR China.ORCID 0000-0002-2416-8110
Chunlian LiState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, PR China.
Jaroslav DoleželInstitute of Experimental Botany of the Czech Academy of Sciences, Centre of Plant Structural and Functional Genomics, Olomouc, Czechia.
Kateřina HolušováJInstitute of Experimental Botany of the Czech Academy of Sciences, Centre of Plant Structural and Functional Genomics, Olomouc, Czechia.
John RathjenResearch School of Biology, Australian National University, Canberra, ACT, Australia.ORCID 0000-0003-4073-8088
Evans LagudahAgriculture and Food, Commonwealth Scientific and Industrial Research Organisation, Canberra, ACT, Australia.ORCID 0000-0002-6234-1789
Xiaojie WangState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, PR China.ORCID 0000-0001-9968-0373
Zhensheng KangState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, PR China. kangzs@nwafu.edu.cn.ORCID 0000-0001-5575-0122
Sambasivam PeriyannanAgriculture and Food, Commonwealth Scientific and Industrial Research Organisation, Canberra, ACT, Australia. Sambasivam.Periyannan@unisq.edu.au.ORCID 0000-0002-5421-2872
Dejun HanState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling, PR China. handj@nwafu.edu.cn.ORCID 0000-0002-4885-7359
Qingdong ZengState Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, PR China. zengqd@nwafu.edu.cn.ORCID 0000-0002-7856-2340

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32272088National Natural Science Foundation of China (National Science Foundation of China) 32293240National Natural Science Foundation of China (National Science Foundation of China) 32302377National Natural Science Foundation of China (National Science Foundation of China) 32372562
6 · The paper itself

Abstract

Stripe or yellow rust (YR), caused by Puccinia striiformis Westend. f. sp. tritici (Pst), is a devastating fungal disease of wheat. Here, we report the map-based cloning of Yr26 (synonyms: Yr24, YrCH42, and YrG22), a major stripe rust resistance gene, and its validation by gene silencing, mutation analysis and transgenic complementation. Yr26, which firstly arises in emmer wheat and recently has introgressed into bread wheat, is a newly evolved gene encoding a transmembrane protein. AlphaFold v3.0 predictes a C-terminal four-helical bundle domain that is critical for triggering Ca

Indexed as

BasidiomycotaDisease ResistanceMembrane ProteinsPlant DiseasesPlant ProteinsPucciniaTriticumAmino Acid SequenceCloning, MolecularGene SilencingPlants, Genetically ModifiedMembrane ProteinsPlant Proteins

Identifiers

PMID42816488
PMCPMC13627085

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.