Evidence map›Paper›PMID 42816095›Full record

ArticleBMJ open2026

Reproducible study identification and selection in systematic reviews: barriers and paths forward.

Lifeng Lin, Xing Xing, Chong Wu, Yiqun Chen, Jiayi Tong, Deborah Jean McClelland, Zhao Chen

Abstract read
In one paragraph

Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lifeng LinDepartment of Epidemiology and Biostatistics, The University of Arizona, Tucson, Arizona, USA lifenglin@arizona.edu.ORCID http://orcid.org/0000-0002-3562-9816
Xing XingDepartment of Epidemiology and Biostatistics, The University of Arizona, Tucson, Arizona, USA.
Chong WuDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Yiqun ChenDepartment of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Jiayi TongDepartment of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Deborah Jean McClellandHealth Science Library, The University of Arizona, Tucson, Arizona, USA.ORCID http://orcid.org/0000-0003-3679-9435
Zhao ChenDepartment of Epidemiology and Biostatistics, The University of Arizona, Tucson, Arizona, USA.

Funding

Innovative Methods for Next-Generation Evidence Synthesis in Oral Health ResearchR01DE036160 · NIDCR · UNIVERSITY OF ARIZONA · PI Lifeng Lin · 2026 to 2026
$372k
Advanced Methods and Software for Trial Sequential Analysis in Living Systematic ReviewsR21LM014533 · NLM · UNIVERSITY OF ARIZONA · PI LIN, LIFENG · 2024 to 2025
$364k
Innovative Data Integration Models for Handling Evidence Inconsistency in AD/ADRD ResearchR03AG093555 · NIA · UNIVERSITY OF ARIZONA · PI LIN, LIFENG · 2025 to 2025
$301k
NIA NIH HHS R03 AG093555NIDCR NIH HHS R01 DE036160NLM NIH HHS R21 LM014533
6 · The paper itself

Abstract

Systematic reviews are foundational to evidence-based practice, but the reproducibility and auditability of study identification and selection remain persistent challenges. Existing reporting standards, such as Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 and PRISMA-Search extension, have improved transparency, yet important gaps remain in documenting search strategies, retrieved records, screening decisions and supplementary identification methods. In this article, we discuss key barriers to reproducibility, including incomplete or inconsistent search documentation, limitations in date filter precision, restricted access to databases and platforms, non-repeatable supplementary search methods and variability in applying eligibility criteria. We suggest a minimum documentation set specifying the search histories, source-specific exports, record-management information, screening decisions and artificial intelligence (AI)-related records that review teams should preserve and share. We also recommend information-specialist involvement and carefully documented human-in-the-loop AI use. These strategies may not guarantee perfect reproducibility, but they can improve auditability, reduce research waste and strengthen trust in systematic reviews.

Indexed as

Research DesignSystematic Reviews as TopicArtificial IntelligenceHumansReproducibility of ResultsArtificial IntelligenceLiteratureMeta-AnalysisSTATISTICS & RESEARCH METHODSSystematic Review

Identifiers

PMID42816095
PMCPMC13630074

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.