Evidence map›Paper›PMID 42814860›Full record

ArticleChemistry & biodiversity2026

Coumarin-Based Antifungal Leads: Design, Synthesis, Mechanistic Insights, and Synergistic Activity.

Xiangna Chang, Qiang Du, Xiaoying Ma, Jundi Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiangna ChangSchool of Food Science and Engineering, Shaanxi University of Science & Technology, Xi'an, China.
Qiang DuSchool of Food Science and Engineering, Shaanxi University of Science & Technology, Xi'an, China.
Xiaoying MaSchool of Food Science and Engineering, Shaanxi University of Science & Technology, Xi'an, China.
Jundi ZhangSchool of Food Science and Engineering, Shaanxi University of Science & Technology, Xi'an, China.

Funding

National Natural Science Foundation of China 32572709Shaanxi University of Science and Technology 2022BJ-31Weiyang Technology Bureau of Xi'an 202415
6 · The paper itself

Abstract

To address the challenge of fungicide resistance in plant pathogenic fungi, coumarin derivatives were designed. Two series of coumarin derivatives, including 3-amide and thienocoumarin ether derivatives, were designed and synthesized through structural modification of the coumarin scaffold to explore their antifungal potential. Their antifungal activities were evaluated using the mycelial growth rate method, with half-maximal effective concentration (EC

Indexed as

Antifungal AgentsCoumarinsDrug DesignAscomycotaDose-Response Relationship, DrugDrug SynergismMicrobial Sensitivity TestsMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipAntifungal AgentscoumarinCoumarinsantifungal lead compoundscoumarin derivativemembrane integritymolecular dockingplant pathogenic fungisynergistic interactions

Identifiers

PMID42814860
PMCPMC13626469

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.