Evidence map›Paper›PMID 42814834›Full record

ArticleScience advances2026

Chemo-metallo nanodrivers for spatiotemporally controlled in situ vaccination.

Xianmin Li, Huali Lei, Youdong Chen, Yuqi Yang, Shunyi Lu, Shuguang Han, Shumin Sun, Zifan Pei, Xiaoxiao Pan, Kai Chen and 3 more

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xianmin LiDepartment of Oncology, Suzhou Xiangcheng People's Hospital, Suzhou 215131, China.ORCID 0009-0004-7107-0062
Huali LeiInstitute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory of Advanced Healthcare Materials & Devices, Biomedical Basic Research Center (BBRC) of Jiangsu Province, Soochow University, Suzhou 215123, China.ORCID 0009-0000-8535-8607
Youdong ChenInstitute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory of Advanced Healthcare Materials & Devices, Biomedical Basic Research Center (BBRC) of Jiangsu Province, Soochow University, Suzhou 215123, China.ORCID 0009-0000-8366-0124
Yuqi YangInstitute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory of Advanced Healthcare Materials & Devices, Biomedical Basic Research Center (BBRC) of Jiangsu Province, Soochow University, Suzhou 215123, China.
Shunyi LuInstitute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory of Advanced Healthcare Materials & Devices, Biomedical Basic Research Center (BBRC) of Jiangsu Province, Soochow University, Suzhou 215123, China.ORCID 0009-0007-8045-5855
Shuguang HanDepartment of Gastrointestinal Surgery, Suzhou Xiangcheng People's Hospital, Suzhou 215131, China.
Shumin SunInstitute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory of Advanced Healthcare Materials & Devices, Biomedical Basic Research Center (BBRC) of Jiangsu Province, Soochow University, Suzhou 215123, China.ORCID 0009-0004-5449-0874
Zifan PeiInstitute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory of Advanced Healthcare Materials & Devices, Biomedical Basic Research Center (BBRC) of Jiangsu Province, Soochow University, Suzhou 215123, China.ORCID 0009-0001-6166-9678
Xiaoxiao PanInstitute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory of Advanced Healthcare Materials & Devices, Biomedical Basic Research Center (BBRC) of Jiangsu Province, Soochow University, Suzhou 215123, China.
Kai ChenDepartment of Oncology, The First Affiliated Hospital of Soochow University, Suzhou 215031, China.ORCID 0009-0006-8724-0948
Lian LianDepartment of Oncology, Suzhou Xiangcheng People's Hospital, Suzhou 215131, China.ORCID 0000-0002-8620-0374
Guanghui HouInstitute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory of Advanced Healthcare Materials & Devices, Biomedical Basic Research Center (BBRC) of Jiangsu Province, Soochow University, Suzhou 215123, China.ORCID 0009-0008-8939-1816
Liang ChengInstitute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory of Advanced Healthcare Materials & Devices, Biomedical Basic Research Center (BBRC) of Jiangsu Province, Soochow University, Suzhou 215123, China.ORCID 0000-0001-5324-9094

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In situ cancer vaccines exhibit promising therapeutic potential; however, their efficacy is constrained by limited antigen release, suboptimal spatiotemporal immune coordination, and adaptive immune resistance. In this study, we identify zinc ions (Zn

Indexed as

Cancer VaccinesAnimalsAntineoplastic AgentsCell Line, TumorcGAS-STING Signaling PathwayCisplatinHumansMiceNanovaccinesVaccinationZincAntineoplastic AgentsCancer VaccinesCisplatinNanovaccinesZinc

Identifiers

PMID42814834
PMCPMC13626044

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.