Evidence map›Paper›PMID 42814826›Full record

ArticleScience advances2026

A NIR-II AIEgen with superior fluorescence and photothermal performance for precision theranostics.

Huanlong Zheng, Tiantian Li, Tong Sun, Jiahang Xu, Jinbei Wei, Shi-Tong Zhang, Chenguang Wang, Dongxu Wang, Geyu Lu, Ben Zhong Tang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Huanlong ZhengState Key Laboratory of Integrated Optoelectronics, Key Laboratory of Advanced Gas Sensors of Jilin Province, College of Electronic Science and Engineering, College of Integrated Circuits, Jilin University, Changchun 130012, China.ORCID 0009-0002-0191-0965
Tiantian LiLaboratory Animal Center, College of Animal Science, Jilin University, Changchun 130021, China.
Tong SunDepartment of Breast Surgery, China-Japan Union Hospital of Jilin University, Jilin University, Changchun 130033, China.
Jiahang XuState Key Laboratory of Integrated Optoelectronics, Key Laboratory of Advanced Gas Sensors of Jilin Province, College of Electronic Science and Engineering, College of Integrated Circuits, Jilin University, Changchun 130012, China.
Jinbei WeiState Key Laboratory of Integrated Optoelectronics, Key Laboratory of Advanced Gas Sensors of Jilin Province, College of Electronic Science and Engineering, College of Integrated Circuits, Jilin University, Changchun 130012, China.ORCID 0000-0002-5977-5527
Shi-Tong ZhangCollege of Chemistry, Jilin University, Changchun 130012, China.
Chenguang WangState Key Laboratory of Integrated Optoelectronics, Key Laboratory of Advanced Gas Sensors of Jilin Province, College of Electronic Science and Engineering, College of Integrated Circuits, Jilin University, Changchun 130012, China.ORCID 0000-0001-9770-1062
Dongxu WangLaboratory Animal Center, College of Animal Science, Jilin University, Changchun 130021, China.ORCID 0000-0003-0464-1596
Geyu LuState Key Laboratory of Integrated Optoelectronics, Key Laboratory of Advanced Gas Sensors of Jilin Province, College of Electronic Science and Engineering, College of Integrated Circuits, Jilin University, Changchun 130012, China.ORCID 0000-0003-1958-2867
Ben Zhong TangGuangdong Basic Research Center of Excellence for Aggregate Science, School of Science and Engineering, The Chinese University of Hong Kong (Shenzhen), Shenzhen 518172, Guangdong, China.ORCID 0000-0002-0293-964X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Second near-infrared (NIR-II; 1000 to 1700 nanometers) aggregation-induced emission luminogens (AIEgens) hold great promise for imaging-guided precision tumor phototherapy yet are limited by the intrinsic trade-off between fluorescence brightness and photothermal performance. Existing design strategies often yield complex molecular structures while inadequately addressing this trade-off. Herein, we propose a "Minor Tweaks, Major Leaps" concept: Simple modification of the star NIR-II AIEgen

Indexed as

Fluorescent DyesNeoplasmsPhotothermal TherapyPrecision MedicineTheranostic NanomedicineAnimalsCell Line, TumorFluorescenceHumansInfrared RaysMiceNanoparticlesOptical ImagingFluorescent Dyes

Identifiers

PMID42814826
PMCPMC13626042

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.