Evidence map›Paper›PMID 42814805›Full record

ArticleScience advances2026

Population connective field modeling reveals proto-retinotopic visual cortex organization in the prenatal human brain.

So-Hyeon Yoo, Anne-Sophie Kieslinger, Michael A Skeide

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

So-Hyeon YooResearch Group Learning in Early Childhood, Max Planck Institute for Human Cognitive and Brain Sciences, 04103, Leipzig, Germany.ORCID 0000-0001-7442-2511
Anne-Sophie KieslingerResearch Group Learning in Early Childhood, Max Planck Institute for Human Cognitive and Brain Sciences, 04103, Leipzig, Germany.
Michael A SkeideResearch Group Learning in Early Childhood, Max Planck Institute for Human Cognitive and Brain Sciences, 04103, Leipzig, Germany.ORCID 0000-0001-5027-2811

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The visual space is sampled by cortical field maps in which nearby neuronal populations encode nearby locations of images received from the retina. Whether retinotopic cortical organization already emerges in the neonatal or even prenatal human brain is currently unknown. To answer this question in vivo, we applied population connective field modeling to 871 resting-state functional magnetic resonance imaging datasets ranging from prenatal to young adult age. We found topographically organized eccentricity and polar angle connectivity maps in V2 and V3 of the visual cortex as early as the 21st week of gestation. These results highlight that human proto-retinotopic cortical maps develop in the second trimester of pregnancy, predating visual experience.

Indexed as

RetinaVisual CortexAdultBrain MappingFemaleHumansMagnetic Resonance ImagingPregnancyYoung Adult

Identifiers

PMID42814805
PMCPMC13626056

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.