Evidence map›Paper›PMID 42814772›Full record

ArticlePLoS computational biology2026

Context-dependent feature modulation shapes human decision policies in approach-avoidance conflicts.

Sergej A E Golowin, Niall W Duncan, Faizan Shaikh, Christoph W Korn

Abstract read
In one paragraph

Article in PLoS computational biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sergej A E GolowinSection Social Neuroscience, Department of General Psychiatry, University of Heidelberg, Heidelberg, Germany.ORCID https://orcid.org/0000-0001-8848-8044
Niall W DuncanGraduate Institute of Mind, Brain and Consciousness, Taipei Medical University, Taipei, Taiwan.ORCID https://orcid.org/0000-0002-3225-9119
Faizan ShaikhSection Social Neuroscience, Department of General Psychiatry, University of Heidelberg, Heidelberg, Germany.
Christoph W KornSection Social Neuroscience, Department of General Psychiatry, University of Heidelberg, Heidelberg, Germany.ORCID https://orcid.org/0000-0002-8228-2624

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sequential decisions often involve trade-offs between immediate rewards and future risks, particularly in approach-avoidance contexts. While such behavior is commonly framed in terms of optimization principles, it remains unclear how decision processes adapt across contexts. We developed a sequential foraging task in which participants made binary choices under probabilistic reward and predation risk (threat). The design dissociated reward probability from threat and enabled formal comparison of policies based on decision-relevant features (e.g., reward and threat probabilities), a multi-feature policy, and a mathematically optimal policy derived from a fully observable Markov Decision Process. Crucially, the task included two implicitly signaled conditions - approach and avoidance - that differed in how reward and threat information jointly shaped the optimal policy. In both conditions, higher reward probabilities were associated with higher predation risk. However, the balance between these competing factors differed across environments, creating contexts in which the optimal policy either favored approaching or avoiding the higher-threat option. Behavior was analyzed using hierarchical Bayesian models capturing both individual decision features and optimal action values, as well as their modulation by task context. Avoidance contexts selectively altered the weighting of decision features, with reduced reliance on reward probability. In addition, choices showed evidence for increased alignment with optimal state-action values, even after accounting for single feature policies within a shared model. This indicates that behavior more strongly reflected the value structure of the environment under avoidance, consistent with enhanced integration of decision-relevant features. These findings suggest that adaptive behavior in sequential decision-making arises from context-dependent feature reweighting alongside increased alignment with integrated value signals. This provides a parsimonious account of how humans adjust decision-making under threat, without requiring assumptions about discrete strategy shifts.

Indexed as

Avoidance LearningDecision MakingAdultBayes TheoremChoice BehaviorComputational BiologyFemaleHumansMaleMarkov ChainsRewardRisk-Taking

Identifiers

PMID42814772
PMCPMC13652344

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.