Evidence map›Paper›PMID 42814764›Full record

ArticleeLife2026

Zinc is a key regulator of the sperm-specific K

Rizki Tsari Andriani, Tanadet Pipatpolkai, Haruhiko Miyata, Masahito Ikawa, Yasushi Okamura, Takafumi Kawai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rizki Tsari AndrianiIntegrative Physiology, Graduate School of Medicine, The University of Osaka, Suita, Japan.ORCID https://orcid.org/0000-0002-9242-469X
Tanadet PipatpolkaiSchool of Physical and Mathematical Science, Nanyang Technological University, Singapore, Singapore.ORCID https://orcid.org/0000-0001-5396-4784
Haruhiko MiyataResearch Institute for Microbial Diseases, The University of Osaka, Suita, Japan.ORCID https://orcid.org/0000-0003-4758-5803
Masahito IkawaResearch Institute for Microbial Diseases, The University of Osaka, Suita, Japan.ORCID https://orcid.org/0000-0001-9859-6217
Yasushi OkamuraIntegrative Physiology, Graduate School of Medicine, The University of Osaka, Suita, Japan.ORCID https://orcid.org/0000-0001-5386-7968
Takafumi KawaiIntegrative Physiology, Graduate School of Medicine, The University of Osaka, Suita, Japan.ORCID https://orcid.org/0000-0001-6632-5551

Funding

Fusion Oriented REsearch for disruptive Science and Technology 10.52926/jpmjfr225zJapan Society for the Promotion of Science 19H03401Japan Society for the Promotion of Science 22H02804Japan Society for the Promotion of Science JP17K15558Japan Society for the Promotion of Science JP23K06334Japan Society for the Promotion of Science JSPS Postdoctoral Fellowship for Research in JapanMinistry of Education, Culture, Sports, Science and Technology 25H01334Ministry of Education, Culture, Sports, Science and Technology JP20H05507Ministry of Education, Culture, Sports, Science and Technology JP20H05791Ministry of Education, Culture, Sports, Science and Technology JP22K15074Nanyang Technological University Lee Kuan Yew Postdoctoral Fellowship
6 · The paper itself

Abstract

The voltage- and pH-gated Slo3 potassium channel is exclusively expressed in mammalian spermatozoa. Its sensitivity to both voltage and alkalization plays a crucial role in sperm fertility, which is tightly coupled to the capacitation process. Here, we show that sperm-enriched divalent cation Zn

Indexed as

Large-Conductance Calcium-Activated Potassium ChannelsSpermatozoaSperm CapacitationZincAnimalsMaleMiceOocytesSperm ProteinsXenopus laevisKcnu1 protein, mouseLarge-Conductance Calcium-Activated Potassium ChannelsSperm ProteinsZinccapacitationcell biologydevelopmental biologymousepatch-clamp methodologypotassium channelspermvoltage clamp fluorometryvoltage-gated ion channelxenopus

Identifiers

PMID42814764
PMCPMC13626651

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.