Evidence map›Paper›PMID 42814680›Full record

ArticlePloS one2026

The moderating role of impulsivity in the association between sexual abuse and substance use frequency across countries, gender identities, and sexual orientations.

Damla E Aksen, Marc N Potenza, Sarah D Lichenstein, Léna Nagy, Shane W Kraus, Joël Billieux, Loïs Fournier, Zsolt Demetrovics, Mónika Koós, International Sex Survey Consortium and 1 more

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Damla E AksenRadiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, United States of America.
Marc N PotenzaYale University School of Medicine, New Haven, Connecticut, United States of America.ORCID https://orcid.org/0000-0002-6323-1354
Sarah D LichensteinDepartment of Psychiatry, Yale School of Medicine, New Haven, Connecticut, United States of America.
Léna NagyDoctoral School of Psychology, ELTE Eötvös Loránd University, Budapest, Hungary.ORCID https://orcid.org/0000-0002-7947-2988
Shane W KrausDepartment of Psychology, University of Nevada, Las Vegas, Nevada, United States of America.
Joël BillieuxInstitute of Psychology, University of Lausanne, Lausanne, Switzerland.
Loïs FournierInstitute of Psychology, University of Lausanne, Lausanne, Switzerland.ORCID https://orcid.org/0000-0001-6743-6456
Zsolt DemetrovicsFlinders University Institute for Mental Health and Wellbeing, College of Education, Psychology and Social Work, Flinders University, Bedford Park, South Australia, Australia.
Mónika KoósInstitute of Forensic Psychiatry and Sex Research, Center for Translational Neuro-and Behavioral Science, University of Duisburg-Essen, Essen, Germany.ORCID https://orcid.org/0000-0002-9961-9174
International Sex Survey Consortium
Beáta BőtheDépartement de Psychologie, Université de Montréal, Montréal, Canada.

Funding

Neuroimaging Sciences Training ProgramT32DA022975 · NIDA · YALE UNIVERSITY · PI Graeme F Mason, Rajita Sinha · 2007 to 2026
$5.7M
Connectome-based neuromarkers of problem cannabis useK08DA051667 · NIDA · YALE UNIVERSITY · PI LICHENSTEIN, SARAH D. · 2020 to 2024
$959k
NIDA NIH HHS K08 DA051667NIDA NIH HHS T32 DA022975
6 · The paper itself

Abstract

This study examined how impulsivity moderates the relationship between sexual abuse and substance use frequency in a large international sample. Participants (N = 64,472) completed the Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST-11), the UPPS-P Impulsive Behavior Scale, and sexual abuse measures through the International Sex Survey. Structural equation models tested associations between childhood sexual abuse (CSA), adolescent/adult sexual abuse (AASA), and combined exposure with substance use frequency, and explored moderation by impulsivity across gender identity, sexual orientation, and country. AASA and CSA+AASA were consistently associated with higher substance use frequency, while CSA alone showed weaker or inconsistent associations across groups. Urgency and premeditation facets of impulsivity moderated these associations, particularly among sexual and gender minority individuals. Country-level differences indicated cultural and contextual variation in how impulsivity interacts with trauma to influence substance use. Findings underscore the need for targeted, culturally responsive interventions addressing impulsivity in the aftermath of sexual trauma.

Indexed as

Child Abuse, SexualGender IdentityImpulsive BehaviorSex OffensesSexual BehaviorSubstance-Related DisordersAdolescentAdultFemaleHumansMaleYoung Adult

Identifiers

PMID42814680
PMCPMC13626376

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.