Evidence map›Paper›PMID 42814628›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Blue Light Receptor PHR2-Mediated Spectrum Antiviral Immunity.

Runyi Chen, Yuxin Tai, Xinyu Wang, Chunhua Mu, Xia Liu, Gongjian Li, Jiayi Liu, Xin Lu, Duo Shi, Zhiqiang Zhou and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Runyi Chen *State Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Yuxin Tai *State Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.ORCID https://orcid.org/0000-0003-4932-3938
Xinyu WangState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Chunhua MuShandong Academy of Agricultural Sciences, Jinan, China.
Xia LiuShandong Academy of Agricultural Sciences, Jinan, China.
Gongjian LiState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Jiayi LiuState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Xin LuState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Duo ShiHinggan League Academy of Agricultural and Animal Husbandry Sciences, Hinggan League, China.
Zhiqiang ZhouState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Jienan HanState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Zhuanfang HaoState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Mingshun LiState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Degui ZhangState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Hongjun YongState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Zhennan XuState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Jianfeng WengState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.ORCID https://orcid.org/0000-0002-4798-6351
Xinhai LiState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.

Funding

Agriculture Science and Technology Major ProjectCentral Public-interest Scientific Institution Basal Research Fund Y2026FZ15Inner Mongolia Innovation Center of Biological Breeding Technology CAAS-CSCB-202403Modern Agro-Industry Technology Research System of Maize CARS-02-02National Key Research and Development Program of China 2022YFD1201802
6 · The paper itself

Abstract

Plant viruses have evolved sophisticated virulence strategies to counteract host antiviral defenses. Blue light, as an important environmental signal, can regulate plant growth and tolerance to biological stress. Nevertheless, how blue light regulates plant responses to antiviral immunity remains largely obscure. Here, we demonstrate that blue light suppresses rice black-streaked dwarf virus (RBSDV) replication. The blue light receptor ZmPHR2 functions as a key immune component, positively regulating maize resistance to RBSDV. Mechanistically, ZmPHR2 interacts with ZmISP in chloroplasts to trigger a defensive reactive oxygen species (ROS) burst, thereby conferring resistance. The RBSDV effector P6 enhances the ZmPHR2-ZmISP interaction, alters their subcellular distribution, and suppresses ROS accumulation. A functionally analogous P6-OsPHR2-OsISP module similarly mediates RBSDV resistance in rice. Our findings reveal that blue light perception directly activates antiviral defense pathways, uncovering a molecular basis for RBSDV resistance. This study provides a theoretical basis for artificially modifying the blue light receptor protein to enhance the resistance of cereal crops.

Indexed as

blue lightISPPHR2reactive oxygen speciesrice black streaked dwarf virus

Identifiers

PMID42814628
PMCPMC13626285

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.