Evidence map›Paper›PMID 42814591›Full record

Observational studyBJS open2026

Association of the Flemish Triage Risk Screening Tool with postoperative outcomes in older adults after colorectal cancer surgery: retrospective cohort study.

Federico Ghignone, Giampaolo Ugolini, Isacco Montroni, Filippo Banchini, Fausto Catena, Davide Cavaliere, Giorgio Ercolani, Gianluca Garulli, Andrea Lucchi, Valentina Danesi and 8 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BJS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Federico GhignoneColorectal and General Surgery Unit, 'Santa Maria delle Croci' Hospital, Ravenna, Italy.
Giampaolo UgoliniColorectal and General Surgery Unit, 'Santa Maria delle Croci' Hospital, Ravenna, Italy.
Isacco MontroniColorectal Cancer Unit, 'Istituto Nazionale Tumori', Milan, Italy.
Filippo BanchiniDepartment of Surgery, 'Guglielmo Da Saliceto' Hospital, Piacenza, Italy.
Fausto CatenaDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.
Davide CavaliereGeneral Surgery Unit, 'Degli Infermi' Hospital, Faenza, Italy.
Giorgio ErcolaniDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.
Gianluca GarulliGeneral Surgery Unit, 'Infermi' Hospital, Rimini, Italy.
Andrea LucchiGeneral Surgery Unit, 'Ceccarini' Hospital, Riccione, Italy.
Valentina DanesiData Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy.
Ilaria MassaData Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy.ORCID 0000-0003-1388-3175
Parisa SoleimaniDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.
William BalziData Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy.
Alice AndalòData Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy.
Martina CavallucciData Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy.
Nicola GentiliData Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy.
Andrea RoncadoriData Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy.
ESCA Collaborative Group

Funding

Italian Ministry of Health 'Ricerca Corrente'
6 · The paper itself

Abstract

backgroundOlder adults undergoing colorectal cancer (CRC) surgery are at increased risk of postoperative complications, mortality, and loss of independence. Frailty screening tools may support perioperative risk stratification. This study evaluated the association between the Flemish Triage Risk Screening Tool (fTRST) and postoperative outcomes.

methodsThis retrospective multicentre cohort study analysed the Emilia-Romagna Surgical Colorectal Audit. Patients aged ≥ 70 years undergoing CRC surgery (2019-2023) were included. Patients with fTRST scores ≥ 2 and < 2 were matched 1 : 1 using propensity score matching. Primary outcomes were 30-, 90-, and 180-day mortality and complications. Secondary outcomes included prolonged hospital stay and discharge to a non-independent setting. Logistic regression and receiver operating characteristic (ROC) curve analyses were performed.

resultsIn all, 1539 patients were included in the study. Mortality at 30, 90, and 180 days was 4.2%, 7.1%, and 10.5%, respectively. In the unmatched cohort, each 1-point increase in fTRST score was significantly associated with 30-day mortality (odds ratio (OR) 1.36; 95% confidence interval (c.i.) 1.12 to 1.66), complications (OR 1.12; 95% c.i. 1.02 to 1.23), prolonged hospital stay (OR 1.13; 95% c.i. 1.03 to 1.24), and discharge to a non-independent setting (OR 1.35; 95% c.i. 1.21 to 1.51). After matching 566 pairs, higher fTRST score remained significantly associated with 30-day mortality (OR 1.33; 95% c.i. 1.09 to 1.63) and discharge to a non-independent setting (OR 1.40; 95% c.i. 1.25 to 1.59). ROC analysis using an fTRST cut-off of ≥2 showed moderate discrimination for 30-day mortality and discharge to a non-independent setting, with areas under the ROC curve of 72.4% (negative predictive value 98.2%) and 67.2% (positive predictive value 66.3%), respectively.

conclusionsThe fTRST is a simple screening tool for identifying older adults at risk of adverse postoperative and functional outcomes after CRC surgery, supporting perioperative planning.

Indexed as

Colorectal NeoplasmsPostoperative ComplicationsTriageAgedAged, 80 and overColorectal Surgical ProceduresFemaleFrailtyGeriatric AssessmentHumansLength of StayMaleRetrospective StudiesRisk AssessmentROC Curve

Identifiers

PMID42814591
PMCPMC13625654

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.