ArticleLa Radiologia medica2026
Contrast-enhanced magnetic resonance neurography aids in diagnosis and grading of carpal tunnel syndrome: a preliminary study.
Article in La Radiologia medica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo preliminarily investigate the diagnostic performance of contrast-enhanced magnetic resonance neurography (CE-MRN) for carpal tunnel syndrome (CTS) and evaluate the association between CE-MRN parameters and clinical assessments. MATERIALS AND
methodsThe study involved thirty-one idiopathic CTS patients and thirty healthy controls. Clinical assessments encompassed symptom evaluation and the Boston Carpal Tunnel Questionnaire (BCTQ). On CE-MRN, a "negative enhancement" sign, defined as focal signal reduction in the median nerve, was used to identify entrapment. Median nerve width and nerve-to-muscle T2 signal intensity ratio (nT2) were measured on CE-MRN and non-contrast MRN (ncMRN), and entrapment length was measured on CE-MRN. Routine MRI metrics encompassed cross-sectional area, flattening ratio, bowing ratio, and relative signal intensity. Diagnostic performance and correlations with clinical variables were analyzed.
resultsThe CE-MRN demonstrated a sensitivity of 0.87 and specificity of 0.90 for detecting CTS using "negative enhancement" sign. The combination of nerve width and nT2 on CE-MRN, demonstrated higher diagnostic efficacy for CTS compared to routine MRI and ncMRN (AUC 0.87-0.94 for CE-MRN vs. AUC 0.73-0.91 for ncMRN vs. AUC 0.55-0.86 for routine MRI). Among the CE-MRN metrics, nT2 showed a negative correlation with BCTQ symptom scores, while entrapment length demonstrated a positive correlation with disease duration (p < 0.05).
conclusionsThe "negative enhancement" sign on CE-MRN improves the diagnostic accuracy of idiopathic CTS. CE-MRN, which is characterized by three-dimensional visualization, may offer an innovative and non-invasive visual approach for the clinical diagnosis and evaluation of CTS.
Indexed as
Identifiers
42814275What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.