Evidence map›Paper›PMID 42814228›Full record

Observational studySupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

Early post-operative changes in quality of life and psychological symptoms after breast cancer surgery: the role of perceived pain, upper limb disability, and disease acceptance.

Carlo Lai, Emanuele Giraldi, Teresa Paolucci, Alice Cichelli, Sofia Mazzani, Stefano Delli Pizzi, Giorgio Veneziani, Breast Cancer Unit

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

Carlo LaiDepartment of Dynamic and Clinical Psychology, and Health Studies, Sapienza University of Rome, Via Degli Apuli, 1, 00185, Rome, Italy. carlo.lai@uniroma1.it.ORCID https://orcid.org/0000-0002-7638-0375
Emanuele GiraldiDepartment of Dynamic and Clinical Psychology, and Health Studies, Sapienza University of Rome, Via Degli Apuli, 1, 00185, Rome, Italy.ORCID http://orcid.org/0009-0000-7895-5411
Teresa PaolucciDepartment of Oral Medical Sciences and Biotechnology (DSMOB), "G. d'Annunzio" University of Chieti-Pescara, 66100, Chieti, Italy.ORCID http://orcid.org/0009-0000-3410-4834
Alice CichelliDepartment of Theoretical and Applied Sciences (DiSTA), eCampus University, 22060, Novedrate, Italy.ORCID http://orcid.org/0009-0003-1170-3932
Sofia MazzaniDepartment of Dynamic and Clinical Psychology, and Health Studies, Sapienza University of Rome, Via Degli Apuli, 1, 00185, Rome, Italy.ORCID http://orcid.org/0009-0006-3027-1014
Stefano Delli PizziDepartment of Neuroscience, Imaging, and Clinical Sciences, University «G. d'Annunzio» of Chieti-Pescara, 66100, Chieti, Italy.ORCID http://orcid.org/0000-0003-4075-0132
Giorgio VenezianiDepartment of Dynamic and Clinical Psychology, and Health Studies, Sapienza University of Rome, Via Degli Apuli, 1, 00185, Rome, Italy.ORCID http://orcid.org/0000-0001-6223-5460
Breast Cancer Unit

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe present study aimed to evaluate changes in QoL and psychological symptoms (anxiety and depression) in women with BC between the first days (T0) and 1 month after surgery (T1). In addition, the study examined longitudinal associations of perceived pain, upper limb disability, and disease acceptance with QoL and psychological symptoms across T0 and T1.

methodsA prospective, observational cohort study was conducted on 101 women with BC. At T0 and T1, the EuroQol Five-Dimension Five-Level, the Hospital Anxiety and Depression Scale, the Numeric Rating Scale, the Quick Disability of the Arm, Shoulder and Hand, and an adapted version of the Chronic Pain Acceptance Questionnaire were administered. Data were analyzed using paired-samples t-tests and linear mixed models (LMMs).

resultsThe results showed increased QoL and decreased psychological symptoms between T0 and T1. The LMMs revealed that assessment time was not significantly associated with QoL and psychological symptoms once perceived pain, upper limb disability, and disease acceptance were considered. Notably, perceived pain and upper limb disability were negatively associated with QoL. In addition, upper limb disability was positively associated with depressive symptoms. Lastly, disease acceptance was negatively associated with both anxiety and depressive symptoms.

conclusionImprovements in QoL and psychological symptoms may occur within the first month after BC surgery. At equivalent levels of perceived pain, upper limb disability, and disease acceptance, the timing of assessment seems to provide no additional information about QoL and psychological symptoms. The findings suggest the importance of timely, multidisciplinary rehabilitation care for women with BC during the early post-operative period.

Indexed as

Breast NeoplasmsQuality of LifeAdultAgedAnxietyDepressionFemaleHumansLongitudinal StudiesMiddle AgedPostoperative PeriodProspective StudiesSurveys and QuestionnairesTime FactorsUpper ExtremityBreast cancerDisease acceptancePainPsychological symptomsQuality of lifeUpper limb disability

Identifiers

PMID42814228
PMCPMC13627206

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.