Evidence map›Paper›PMID 42814225›Full record

ReviewDiscover nano2026

From imaging enhancement to surgical autonomy: the evolutionary role of nanotechnology in AI-driven robotic surgery.

Jiahao Zhu, Shengcheng Tai, Zhihang Zhang, Rui-Cheng Wu, Deng-Xiong Li, Xiaodong Jin

Abstract readReview
In one paragraph

Review in Discover nano, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jiahao Zhu *Department of Urology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Shengcheng Tai *Department of Urology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Zhihang Zhang *Department of Urology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Rui-Cheng WuDivision of Surgery & Interventional Science, University College London, London, W1W 7TS, UK. ruicheng.wu@ucl.ac.uk.
Deng-Xiong LiDepartment of Urology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China. dengxiongli@zcmu.edu.cn.
Xiaodong JinDepartment of Urology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China. 20233003@zcmu.edu.cn.

Funding

Clinical efficacy of a Chinese patent medicine combined with L-carnitine in the treatment of prostatitis complicated by asthenospermia 2B12442Clinical Research Program of Traditional Chinese Medicine of the Zhejiang Provincial Administration of Traditional Chinese Medicine 2025ZL262Health Innovation Talent Program / Modernization Capacity Enhancement for High-Quality Development of Public Hospitals 1S22513Zhejiang Provincial Traditional Chinese Medicine Service Capacity Building Project 2A12510
6 · The paper itself

Abstract

Robot-assisted minimally invasive surgery provides stable visualisation and manipulation, but direct access to local tissue state remains limited. Lesion boundaries, mechanics, molecular activity and microenvironmental changes are often inferred from conventional feedback. This review evaluates how nano-enabled imaging, flexible and local sensing, and micro/nanorobotic intervention may extend signals and localised actions in robot-assisted procedures. We organise the evidence along an information-flow framework: signal acquisition, processing or computational interpretation, task-relevant state estimation, conversion into a decision variable or control-relevant input, and feedback-guided robotic action. Processing may involve calibration, signal processing, computational modelling, conventional machine learning, deep learning or artificial intelligence (AI)-based methods. The evidence reviewed is strongest for localised signal acquisition and supervised intervention. Selected forms of computational interpretation have been demonstrated, and localisation- or motion-derived geometric states enter feedback controllers in some systems. By contrast, biochemical, spectral, tactile and physiological states are usually displayed, analysed offline or returned through human-facing feedback; they rarely modify an online surgical controller. Closed-loop navigation in phantoms, surrogate-device studies and constrained navigation autonomy therefore represent partial control capabilities, not clinically relevant surgical autonomy. The principal missing transitions are robust validation of task-relevant tissue states, uncertainty-aware conversion of those states into control inputs, and safe action within realistic surgical workflows. Near-term clinical use is more likely to centre on bounded nano-enabled sensing or intervention modules embedded within supervised procedures. Progress towards bounded task autonomy will require reproducibility, material safety, workflow compatibility, explicit human supervision and prospective evidence of patient and task benefits.

Indexed as

Artificial intelligenceClinical translationClosed-loop controlMicro/nanoroboticsMultimodal sensingNanotechnologyRobotic surgerySurgical autonomy

Identifiers

PMID42814225
PMCPMC13627603

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.