Evidence map›Paper›PMID 42813351›Full record

ArticleActa orthopaedica et traumatologica turcica2026

Facet tropism is not associated with lumbar spondylolysis: a computed tomography-based three-dimensional morphometric case-control study.

Muhammed Enes Karataş, Mehmet Akif Çaçan, İsmail Türkten, Kadriye Betül Pençe, Bayram Ufuk Şakul

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Article in Acta orthopaedica et traumatologica turcica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Muhammed Enes KarataşDepartment of Orthopaedics and Traumatology, İstanbul Medeniyet University, İstanbul, Türkiye.ORCID 0000-0003-0995-0953
Mehmet Akif ÇaçanDepartment of Orthopaedics and Traumatology, İstanbul Medipol University, İstanbul, Türkiye.ORCID 0000-0003-2587-6327
İsmail TürktenDepartment of Anatomy, İstanbul Medipol University, İstanbul, Türkiye.ORCID 0000-0003-0787-7000
Kadriye Betül PençeDepartment of Anatomy, İstanbul Medipol University, İstanbul, Türkiye.ORCID 0000-0001-9444-8444
Bayram Ufuk ŞakulDepartment of Anatomy, İstanbul Medipol University, İstanbul, Türkiye.ORCID 0000-0002-5539-2342

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveFacet tropism has been proposed as a morphologic modifier of posterior element loading, but prior evidence in lumbar spondylolysis is inconsistent and often based on 2D measurements. This study aimed to evaluate whether facet tropism differs between patients with lumbar spondylolysis and controls using a CT-based three-dimensional (3D) morphometric workflow with vertebra-anchored reference planes.

methodsThis retrospective case-control study included 39 individuals: 19 with CT-confirmed lumbar spondylolysis and 20 controls (age and sex comparable). Vertebrae L1-L5 were segmented, 3D surface models were generated, and best-fit planes were computed for each superior and inferior facet surface bilaterally. Facet orientation was quantified relative to sagittal, frontal, and transverse planes. Facet tropism (FT) was defined as the absolute right-left difference in facet angles for the same level and facet type; FT presence was descriptively defined as >5, while hypothesis testing used continuous FT values. Group comparisons were performed across L1-L5 and for prespecified lowerlumbar segment metrics (L4-L5 facet-plane mismatch and L5v intra-vertebral mismatch).

resultsSpondylolysis involved L5 in 18/19 patients (4 unilateral, 14 bilateral) and L4 in 1/19. Across L1-L5, facet tropism (FT) did not differ between groups for either superior or inferior facets in any plane (all p > .05). The greatest numerical difference was observed for L5 inferior FT on the sagittal plane (controls 10.38 } 9.40 vs. patients 7.51 } 10.93), but this comparison did not reach statistical significance (p = .092). Lower-lumbar segment-focused mismatch measures also showed no between-group differences (all p > .05). Frontal-plane and sagittal-plane angles showed strong positive correlations in both groups (controls: r = 0.811-0.998; patients: r = 0.851-0.995; all p < .05), whereas transverse-plane parameters showed no meaningful associations.

conclusionUsing CT-based 3D morphometry, no statistically significant association between facet tropism and lumbar spondylolysis was demonstrated in the present study population, and facet tropism did not discriminate cases from controls across lumbar levels or lowerlumbar segmental mismatch metrics. In this cohort, which was predominantly characterized by L5 involvement and frequent bilateral defects, side-to-side facet asymmetry did not appear to represent a major independent morphologic marker when measured with a standardized 3D framework.   Cite this article as: Karatas ME, .a.an MA, Türkten İ, Pen.e KB, Şakul BU. Facet tropism is not associated with lumbar spondylolysis: a computed tomography- based three-dimensional morphometric case-control study. Acta Orthop Traumatol Turc., 2026; 60(4), 1005, doi: 10.5152/j.aott.2026.261005.

Indexed as

Imaging, Three-DimensionalLumbar VertebraeSpondylolysisTomography, X-Ray ComputedTropismZygapophyseal JointAdultAgedCase-Control StudiesFemaleHumansMaleMiddle AgedRetrospective Studies3D morphometryComputed tomographyFacet orientationFacet tropismLumbar spondylolysisPars defect

Identifiers

PMID42813351
PMCPMC13657332

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.