ArticleJournal of the ASEAN Federation of Endocrine Societies2026
Bridging Gaps in Newborn Screening: A Comparative Study of Point-of-Care Testing Versus Traditional Reference Laboratory Method for Congenital Hypothyroidism.
Article in Journal of the ASEAN Federation of Endocrine Societies, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aimed to compare the reliability, agreement, and practical application (turnaround time) of a point-of-care testing (POCT) device using two different reagents versus the traditional reference laboratory method for thyroid-stimulating hormone (TSH) measurement in newborn congenital hypothyroidism screening. Methodology: This prospective cross-sectional method-comparison study included 122 term newborns at a mother and child hospital in Surabaya, Indonesia. Heel-prick capillary blood samples were simultaneously analyzed using the Standard F-200 POCT device with two reagents (Group 1: n = 62, Standard™ F TSH-II; Group 2: n = 60, FastClear F TSHII) and compared to the standard dried blood spot method (GSP Results: Strong positive correlations were observed in both Group 1 (Pearson's r = 0.87, Spearman's ρ = 0.85; Conclusion: POCT devices present a promising alternative to traditional reference screening method for congenital hypothyroidism.
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