Evidence map›Paper›PMID 42812982›Full record

ReviewAllergologie select2026

The involvement of human breastmilk-derived extracellular vesicles in the development of infant atopic sensitization.

Tinevimbo Weidner Baricholo, Amiq Gazdhar, Matthias V Kopp, Emilie Seydoux

Abstract readReview
In one paragraph

Review in Allergologie select, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tinevimbo Weidner BaricholoLung Precision Medicine (LPM), Department for Biomedical Research (DBMR).
Amiq GazdharLung Precision Medicine (LPM), Department for Biomedical Research (DBMR).
Matthias V KoppLung Precision Medicine (LPM), Department for Biomedical Research (DBMR).
Emilie SeydouxLung Precision Medicine (LPM), Department for Biomedical Research (DBMR).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breastmilk, with its unique biological components, is the optimal source of neonatal nutrition, and WHO global feeding guidance recommends that all infants are exclusively breastfed for the first 6 months. The composition of human milk depends on multiple factors such as maternal diet, exposure to pathogens, metabolic or autoimmune disorders, smoking, mental health, and genetics. Breastfeeding not only transfers nutrients to the child, but it also influences the infant immune function, through the transfer of immune cells, antibodies, microbiota from the mother, cytokines, or growth factors. Among these, human milk-derived extracellular vesicles (hMEVs) are emerging as key yet understudied elements in neonatal growth, development, and immunity. This review explores their structure, formation, uptake, and roles in supporting development, modulating immune responses during early life, and influencing allergic outcomes, highlighting their potential significance in infant health.

Indexed as

allergiesasthmaatopic sensitizationbreastfeedingbreastmilkextracellular vesicles

Identifiers

PMID42812982
PMCPMC13621269

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.