Evidence map›Paper›PMID 42812761›Full record

ArticleCancer innovation2026

Evaluating the Performance of Covidence's Artificial Intelligence-Based Screening Function in Cancer Systematic Reviews.

Ashirbani Saha, Xiaomei Yao, Sharan Saravanan, Aditya Misra, Ashley Low, Samya Ali, Mariam Abdelmalek, Shakil Ahmed, Sussman Jonathan

Abstract read
In one paragraph

Article in Cancer innovation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ashirbani SahaDepartment of Oncology McMaster University Hamilton Canada.ORCID https://orcid.org/0000-0002-7650-1720
Xiaomei YaoDepartment of Oncology McMaster University Hamilton Canada.ORCID https://orcid.org/0000-0002-1210-3758
Sharan SaravananDepartment of Health Research Methods, Evidence, and Impact McMaster University Hamilton Canada.
Aditya MisraFaculty of Health Sciences McMaster University Hamilton Canada.
Ashley LowDepartment of Health Research Methods, Evidence, and Impact McMaster University Hamilton Canada.
Samya AliFaculty of Health Sciences McMaster University Hamilton Canada.
Mariam AbdelmalekFaculty of Health Sciences McMaster University Hamilton Canada.
Shakil AhmedDepartment of Health Research Methods, Evidence, and Impact McMaster University Hamilton Canada.
Sussman JonathanDepartment of Oncology McMaster University Hamilton Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Systematic reviews (SRs), often conducted for evidence synthesis, require extensive multistage screening, with Stage-I title/abstract screening being especially time consuming. Covidence systematic review software, a widely used SR platform, has offered artificial intelligence (AI)-assisted Stage-I screening function since 2022. However, this function's performance has not yet been formally compared across heterogeneous, large-scale oncology-focused SRs. Methods: We selected two completed SRs conducted by the Program in Evidence-based Care (PEBC), Ontario, Canada. The first SR (Axilla-BC, Results: When pooling all subset sizes and the Conclusions: In two large oncology-SRs, Covidence's AI-assisted Stage-I screening function demonstrated meaningful potential to reduce reviewer workload and screening time. Nonetheless, Covidence's performance varied notably between reviews, suggesting a possible association between the results and the characteristics of the SR, including topic, methodological complexity, relevance rate, and inclusion rate. Careful human oversight remains essential to ensure that no potentially finally included studies are missed in evidence synthesis, particularly in nuanced or methodologically complex reviews.

Identifiers

PMID42812761
PMCPMC13620284

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.