Evidence map›Paper›PMID 42812561›Full record

ArticleFrontiers in sports and active living2026

Morning or evening? Time of day does not affect body composition, cardiopulmonary performance, and muscle strength responses to combined training in women with obesity.

Yan Leo Melo Vieira, Ana Vitoria Leca, Bruna Tabata Bernardes, Natalia Yumi Noronha, Carolina Batista Simoes, Pedro Henrique Reis Restier Pinheiro, Alicia Alvarenga Fernandes, Igor Jose Soares Rodrigues, Joao Miguel Guimaraes Flora, Lucas Tulio Lacerda and 7 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in sports and active living, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06601660 (Effect of Combined Physical Training At Different Times of the Day on Muscle and Adipose Tissue Remodeling, Metabolism and Physical Performance in Female Mice and Women with Obesity), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06601660 naactive not recruitingnot on this map

Effect of Combined Physical Training At Different Times of the Day on Muscle and Adipose Tissue Remodeling, Metabolism and Physical Performance in Female Mice and Women with Obesity

TypeinterventionalSponsorState University of Minas GeraisRan2024 to 2025Enrolled60ConditionsObesity Type I and II, Obesity and OverweightArmsMorning Physical Training, Night Physical Training, No intervention
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yan Leo Melo VieiraDepartment of Internal Medicine, Ribeirão Preto Medical School, São Paulo University, Ribeirão Preto, Brazil.
Ana Vitoria LecaMultidisciplinary Center for Chronic Non-Communicable Diseases of the Central-West Region of Minas Gerais, State University of Minas Gerais, Divinópolis Campus, Minas Gerais, Brazil.
Bruna Tabata BernardesMultidisciplinary Center for Chronic Non-Communicable Diseases of the Central-West Region of Minas Gerais, State University of Minas Gerais, Divinópolis Campus, Minas Gerais, Brazil.
Natalia Yumi NoronhaDepartment of Internal Medicine, Ribeirão Preto Medical School, São Paulo University, Ribeirão Preto, Brazil.
Carolina Batista SimoesErgogenic & Systemic and Molecular Physiology Research Group (ERGOFIS), School of Physical Education, Physiotherapy and Occupational Therapy, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Pedro Henrique Reis Restier PinheiroMultidisciplinary Center for Chronic Non-Communicable Diseases of the Central-West Region of Minas Gerais, State University of Minas Gerais, Divinópolis Campus, Minas Gerais, Brazil.
Alicia Alvarenga FernandesMultidisciplinary Center for Chronic Non-Communicable Diseases of the Central-West Region of Minas Gerais, State University of Minas Gerais, Divinópolis Campus, Minas Gerais, Brazil.
Igor Jose Soares RodriguesMultidisciplinary Center for Chronic Non-Communicable Diseases of the Central-West Region of Minas Gerais, State University of Minas Gerais, Divinópolis Campus, Minas Gerais, Brazil.
Joao Miguel Guimaraes FloraMultidisciplinary Center for Chronic Non-Communicable Diseases of the Central-West Region of Minas Gerais, State University of Minas Gerais, Divinópolis Campus, Minas Gerais, Brazil.
Lucas Tulio LacerdaMultidisciplinary Center for Chronic Non-Communicable Diseases of the Central-West Region of Minas Gerais, State University of Minas Gerais, Divinópolis Campus, Minas Gerais, Brazil.
Diego Alcantara BorbaMultidisciplinary Center for Chronic Non-Communicable Diseases of the Central-West Region of Minas Gerais, State University of Minas Gerais, Divinópolis Campus, Minas Gerais, Brazil.
Lucas Rios DrummondMultidisciplinary Center for Chronic Non-Communicable Diseases of the Central-West Region of Minas Gerais, State University of Minas Gerais, Divinópolis Campus, Minas Gerais, Brazil.
Michael Jackson Oliveira de AndradeMultidisciplinary Center for Chronic Non-Communicable Diseases of the Central-West Region of Minas Gerais, State University of Minas Gerais, Divinópolis Campus, Minas Gerais, Brazil.
Julio Sergio MarchiniDepartment of Internal Medicine, Ribeirão Preto Medical School, São Paulo University, Ribeirão Preto, Brazil.
Erick P de OliveiraLaboratory of Nutrition, Exercise and Health (LaNES), School of Medicine, Federal University of Uberlândia, Minas Gerais, Brazil.
Dawit Albieiro Pinheiro GonçalvesErgogenic & Systemic and Molecular Physiology Research Group (ERGOFIS), School of Physical Education, Physiotherapy and Occupational Therapy, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Camila Fernanda Cunha BrandaoDepartment of Internal Medicine, Ribeirão Preto Medical School, São Paulo University, Ribeirão Preto, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Obesity is characterized by adipocyte dysfunction, accompanied by impairments in oxidative metabolism and physical function. Although physical training is known to improve oxidative capacity, body composition, and functional performance, the magnitude of these adaptations may be influenced by several modulatory factors. Among these, circadian rhythm has emerged as a potential determinant of exercise-induced adaptations due to daily fluctuations in metabolic and physiological processes; however, its influence in women with obesity remains unclear. Therefore, this study aimed to investigate the effects of combined training performed at different times of the day (morning vs. evening) on body composition, cardiopulmonary performance, and muscle strength in previously untrained women with obesity. Methods: This randomized clinical trial (NCT06601660) included women with obesity (waist circumference ≥88 cm) aged 18-50 years. Participants were randomly assigned to a control group (CG; Results: Significant group-by-period interactions were observed for VO Conclusion: Eight weeks of combined training performed either in the morning or evening improved maximal muscle strength and cardiopulmonary performance in women with obesity, while producing limited changes in body composition and cardiovascular measures. No consistent evidence of superior adaptations according to training time was observed, suggesting that both schedules can effectively promote health-related adaptations.

Indexed as

cardiopulmonary exercise testingcircadian rhythmexercisemuscle strengthphysical fitness

Identifiers

PMID42812561
PMCPMC13619898

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.