Evidence map›Paper›PMID 42812544›Full record

ArticleCureus2026

Critical Rheumatic Mitral Stenosis Unmasked During Pregnancy Complicated by Preeclampsia With Severe Features and Managed With Urgent Balloon Mitral Valvuloplasty.

Umama Gorsi, Nathan Kim, Rishi Sukhija, Julia Kumar, Pooneh Nabavizadeh

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Umama GorsiCardiology, University System of Maryland, Baltimore, USA.
Nathan KimInternal Medicine, Harbor-UCLA Medical Center, Torrance, USA.
Rishi SukhijaCardiology, University of Cincinnati Medical Center, Cincinnati, USA.
Julia KumarInternal Medicine, University of Cincinnati Medical Center, Cincinnati, USA.
Pooneh NabavizadehCardiology, University of Cincinnati Medical Center, Cincinnati, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnancy imposes significant hemodynamic changes that can unmask previously undiagnosed cardiovascular disease and complicate management when concurrent obstetric conditions are present. We present the case of a 32-year-old immigrant woman at 21 weeks' gestation with a limited medical history due to a significant language barrier, who presented with hypertensive crisis and was diagnosed with preeclampsia with severe features. During her evaluation, she developed worsening dyspnea and acute respiratory decompensation. Further cardiac assessment revealed critical rheumatic mitral stenosis, accompanied by severe left atrial enlargement and markedly elevated transmitral gradients. The coexistence of preeclampsia with severe features and critical mitral stenosis posed a complex hemodynamic challenge, leading to flash pulmonary edema and progressive maternal instability. Given the high maternal and fetal risk associated with continued deterioration, a multidisciplinary team involving maternal-fetal medicine, cardiology, interventional cardiology, cardiac anesthesia, and critical care was assembled to determine the optimal treatment strategy. The patient underwent urgent balloon mitral valvuloplasty with atrial septostomy, resulting in marked hemodynamic improvement and resolution of pulmonary edema. Following the procedure, her clinical status stabilized, and she was discharged with close cardiology follow-up. This report highlights the importance of maintaining a high index of suspicion for underlying structural heart disease in pregnant patients presenting with pulmonary edema, particularly when symptoms appear disproportionate to the severity of preeclampsia. It also demonstrates the critical role of multidisciplinary collaboration and timely percutaneous intervention in achieving favorable maternal outcomes in the setting of severe rheumatic mitral stenosis during pregnancy.

Indexed as

mitral valvepregnancypulmonary edemarheumatic heart diseasestenosis

Identifiers

PMID42812544
PMCPMC13620343

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.