Evidence map›Paper›PMID 42812318›Full record

ReviewFrontiers in immunology2026

Muze Huang, Shiyuan Wu, Zi-Han Shen, Sarena Jiayao Zhang, Yaw-Syan Fu, Jingyi Wu

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Muze Huang *School of Medicine, Xiamen University, Xiamen, Fujian, China.
Shiyuan Wu *School of Stomatology, Xiamen Medical College, Xiamen, Fujian, China.
Zi-Han Shen *School of Clinical Medicine, Xiamen Medical College, Xiamen, Fujian, China.
Sarena Jiayao ZhangSchool of Clinical Medicine, Xiamen Medical College, Xiamen, Fujian, China.
Yaw-Syan FuDepartment of Anatomy, School of Basic Medical Science, Xiamen Medical College, Xiamen, Fujian, China.
Jingyi WuSchool of Medicine, Xiamen University, Xiamen, Fujian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global resurgence of syphilis, marked by a dramatic 150% increase in cases over the last decade and the rise of the dominant SS14-Ω strain cluster, represents a critical threat to public health. This review explores the complex molecular mechanisms by which

Indexed as

Central Nervous SystemSyphilisTreponema pallidumAnimalsBlood-Brain BarrierHost-Pathogen InteractionsHumansImmune Evasionblood-brain barrierimmune evasionneurosyphilissuppressive microenvironmentsTreponema pallidum

Identifiers

PMID42812318
PMCPMC13619478

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.