Evidence map›Paper›PMID 42812222›Full record

ArticlebioRxiv : the preprint server for biology2026

Distinct spatial associations of adversity with hippocampal macro- and microstructure in early adolescence.

Mylla Marsiglia, Doruk Yigit Erigüc, Bianca Serio, Meike D Hettwer, Jordan DeKraker, Laura Waite, Felix Hoffstaedter, Boris C Bernhardt, Simon B Eickhoff, Sofie L Valk

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mylla MarsigliaInstitute of Neuroscience and Medicine, Brain & Behavior (INM-7), Research Centre Jü lich, Jü lich, Germany.
Doruk Yigit ErigücInstitute of Neuroscience and Medicine, Brain & Behavior (INM-7), Research Centre Jü lich, Jü lich, Germany.
Bianca SerioInstitute of Neuroscience and Medicine, Brain & Behavior (INM-7), Research Centre Jü lich, Jü lich, Germany.
Meike D HettwerPenn Lifespan Informatics and Neuroimaging Center, University of Pennsylvania, Philadelphia, USA.
Jordan DeKrakerMontreal Neurological Institute and Hospital, McGill University, Montreal, Canada.ORCID 0000-0002-4093-0582
Laura WaiteInstitute of Neuroscience and Medicine, Brain & Behavior (INM-7), Research Centre Jü lich, Jü lich, Germany.
Felix HoffstaedterInstitute of Neuroscience and Medicine, Brain & Behavior (INM-7), Research Centre Jü lich, Jü lich, Germany.ORCID 0000-0001-7163-3110
Boris C BernhardtMontreal Neurological Institute and Hospital, McGill University, Montreal, Canada.ORCID 0000-0001-9256-6041
Simon B EickhoffInstitute of Neuroscience and Medicine, Brain & Behavior (INM-7), Research Centre Jü lich, Jü lich, Germany.
Sofie L ValkInstitute of Neuroscience and Medicine, Brain & Behavior (INM-7), Research Centre Jü lich, Jü lich, Germany.

Funding

Meta-anaylsis in human brain mappingR01MH074457 · NIMH · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI FOX, PETER THORNTON · 2006 to 2024
$10.5M
NIMH NIH HHS R01 MH074457
6 · The paper itself

Abstract

Youth adversity has been associated with alterations in hippocampal structure; however, it remains unclear whether different forms of adversity relate distinctly to its organization across the anterior-posterior and proximal-distal axes. Here, we investigated the associations of different types of adversity with multiple structural properties of the hippocampus in 5,263 early adolescents from the ABCD Study. Hippocampal macrostructure was characterized using volume, thickness, and gyrification, whereas T1w/T2w ratio served as an

Identifiers

PMID42812222
PMCPMC13618420

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.