Evidence map›Paper›PMID 42812218›Full record

ArticlebioRxiv : the preprint server for biology2026

Metabotropic Glutamatergic Signaling Adaptively Controls Trans-thalamic Communication.

Alan Lai, Xiao-Jing Wang

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alan LaiCenter for Neural Science, New York University, New York, 10003, NY, United States.ORCID 0009-0007-3768-9840
Xiao-Jing WangCenter for Neural Science, New York University, New York, 10003, NY, United States.ORCID 0000-0003-3124-8474

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trans-thalamic circuits link cortical regions through higher-order sensory (HOs) thalamic nuclei to support cognition. These circuits are rich with metabotropic glutamate receptors (mGluRs), whose seconds-long dynamics conflict with the thalamus's traditional relay role, leaving their function unknown. Here, we present a model of group I mGluR-mediated suppression of K

Indexed as

dendritic plateau potentialshigher-order thalamusmetabotropic glutamate receptorsperceptionthalamic bursting

Identifiers

PMID42812218
PMCPMC13618427

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.