Evidence map›Paper›PMID 42812214›Full record

ArticleNanotheranostics2026

Distinct Internalization, Acoustic Behavior and Stress Responses to Nanobubbles in Pancreatic Cancer Cells.

Sila Appak-Baskoy, Muhammad Saad Khan, Dhruvi Patel, Monika Lodyga, Agata A Exner, Michael C Kolios, Imogen R Coe

Abstract read
In one paragraph

Article in Nanotheranostics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sila Appak-BaskoyDepartment of Chemistry and Biology, Toronto Metropolitan University, Toronto, ON M5B 2K3, Canada.
Muhammad Saad KhanInstitute for Biomedical Engineering, Science and Technology (iBEST), Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON M5B 1T8, Canada.
Dhruvi PatelDepartment of Chemistry and Biology, Toronto Metropolitan University, Toronto, ON M5B 2K3, Canada.
Monika LodygaKeenan Research Center for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto, ON M5B 1T8, Canada.
Agata A ExnerDepartments of Radiology and Biomedical Engineering, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, United States.
Michael C KoliosInstitute for Biomedical Engineering, Science and Technology (iBEST), Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON M5B 1T8, Canada.
Imogen R CoeDepartment of Chemistry and Biology, Toronto Metropolitan University, Toronto, ON M5B 2K3, Canada.

Funding

Drug-Loaded Nanobubbles for Ultrasound Enhanced Delivery to Colon Cancer Liver MetastasisR01EB028144 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI EXNER, AGATA A · 2019 to 2023
$2.3M
NIBIB NIH HHS R01 EB028144
6 · The paper itself

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers, characterized by an extremely low survival rate once diagnosed. Over 90% of cases harbor activating

Indexed as

Carcinoma, Pancreatic DuctalContrast MediaMicrobubblesPancreatic NeoplasmsCell Line, TumorEndocytosisHumansContrast MediaKRASmacropinocytosisnanobubblePDACultrasound

Identifiers

PMID42812214
PMCPMC13619351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.