Evidence map›Paper›PMID 42812018›Full record

ReviewRevista de neurologia2026

Meningiomas in Elderly Patients: Epidemiology, Clinical Characteristics, Prognostic Factors, and Personalized Treatment Strategies.

Shuaishuai Wu, Jingjing Wang, Liu Zhang, Xiangji Meng, Yanfen Yao, Haiyan Jia, Zongxu Sun, Yahu Bai, Haixia Jin, Lingzhi Li and 1 more

Abstract readReview
In one paragraph

Review in Revista de neurologia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shuaishuai WuDepartment of Intensive Care Medicine, Shandong Provincial Third Hospital, Shandong University, 250100 Jinan, Shandong, China.
Jingjing WangDepartment of Pathology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, 250117 Jinan, Shandong, China.
Liu ZhangDepartment of Neurosurgery, The First Affiliated Hospital of Jinan University, 510632 Guangzhou, Guangdong, China.
Xiangji MengDepartment of Neurosurgery, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, 250117 Jinan, Shandong, China.
Yanfen YaoDepartment of Intensive Care Medicine, Shandong Provincial Third Hospital, Shandong University, 250100 Jinan, Shandong, China.
Haiyan JiaDepartment of Intensive Care Medicine, Shandong Provincial Third Hospital, Shandong University, 250100 Jinan, Shandong, China.
Zongxu SunDepartment of Intensive Care Medicine, Shandong Provincial Third Hospital, Shandong University, 250100 Jinan, Shandong, China.
Yahu BaiDepartment of Intensive Care Medicine, Shandong Provincial Third Hospital, Shandong University, 250100 Jinan, Shandong, China.
Haixia JinDepartment of Intensive Care Medicine, Shandong Provincial Third Hospital, Shandong University, 250100 Jinan, Shandong, China.
Lingzhi LiDepartment of Intensive Care Medicine, Shandong Provincial Third Hospital, Shandong University, 250100 Jinan, Shandong, China.
Changli WangDepartment of Pathology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, 250117 Jinan, Shandong, China.

Funding

Collaborative Academic Innovation Project of Shandong Cancer Hospital FC002Natural Science Foundation of Shandong Province ZR2024QH188Project of Guangdong Medical Science and Technology Research Foundation A2023443Shandong Cancer Hospital Youth Talent Cultivation Program - Sailing Plan qh-202510
6 · The paper itself

Abstract

As the global population ages, the incidence of meningiomas rises, and the demand for clinical management of elderly patients also rises. Meningiomas are common intracranial tumors, and their incidence increases with age. Elderly patients with meningiomas are prone to comorbidities, reduced reserve function, atypical manifestations, increased perioperative risks, and impaired functional recovery, making management more difficult. The application of neuroimaging leads to more elderly patients with asymptomatic or incidentally discovered meningiomas. Choosing the best strategy among monitoring, surgery, radiotherapy, and other strategies is therefore key to clinical decision-making. For asymptomatic, small, and radiologically low-risk meningiomas in elderly patients, active surveillance is generally the preferred initial strategy. Surgery is more appropriate for symptomatic tumors, lesions with mass effect, documented growth, progressive peritumoral edema, neurological deterioration, or other high-risk clinical and radiological features. However, the treatment goal for elderly patients should emphasize symptom relief, preservation of neurological function, and quality of life more than pursuing gross total resection as routine. Stereotactic radiosurgery and fractionated radiotherapy provide important supplementary treatments for very elderly patients, high surgical risk patients, and postoperative residual lesions. This article reviews recent advances in understanding meningiomas in elderly and very elderly patients, focuses on epidemiology, clinical characteristics, prognostic factors, and treatment strategies, and also discusses the core principles of individualized management for this population to guide clinical practice.

Indexed as

Meningeal NeoplasmsMeningiomaAgedHumansPrecision MedicinePrognosisRadiosurgeryagedfrailtymeningiomaprognosistreatment outcome

Identifiers

PMID42812018
PMCPMC13653187

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.