Evidence map›Paper›PMID 42811420›Full record

ArticleJournal of insect science (Online)2026

Exploring the multigenerational effects of Lippia adoensis (Lamiales: Verbenaceae) essential oil and Dichlorvos on Callosobruchus maculatus (Coleoptera: Bruchidae) life-history traits and gene expression.

Mazarin Akami, Wei Jiang, Bingbing Wei, Ousman Tamgue, Cabrel Bafong Ngueya, Diane Pocssie Samenoug, Francioli Koro Koro, Rosalie Annie Ngono Ngane, Nicolas Njintang Yanou, Elias Nchiwan Nukenine and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of insect science (Online), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mazarin AkamiDepartment of Biochemistry, Faculty of Science, University of Douala, P.O. Box 24, 157, Douala, Cameroon.ORCID 0000-0003-2162-2119
Wei JiangXianghu Laboratory, Hangzhou, 311231, China.ORCID 0000-0002-5473-0223
Bingbing WeiCollege of Plant Science & Technology, Huazhong Agricultural University, No. 1 Shizishan Street, Wuhan 430070, China.ORCID 0009-0008-4387-7693
Ousman TamgueDepartment of Biochemistry, Faculty of Science, University of Douala, P.O. Box 24, 157, Douala, Cameroon.ORCID 0000-0001-6991-8088
Cabrel Bafong NgueyaDepartment of Biochemistry, Faculty of Science, University of Douala, P.O. Box 24, 157, Douala, Cameroon.
Diane Pocssie SamenougDepartment of Biochemistry, Faculty of Science, University of Douala, P.O. Box 24, 157, Douala, Cameroon.
Francioli Koro KoroDepartment of Biochemistry, Faculty of Science, University of Douala, P.O. Box 24, 157, Douala, Cameroon.
Rosalie Annie Ngono NganeDepartment of Biochemistry, Faculty of Science, University of Douala, P.O. Box 24, 157, Douala, Cameroon.ORCID 0000-0003-2216-0366
Nicolas Njintang YanouDepartment of Biological Sciences, Faculty of Science, University of Ngaoundere, Ngaoundere, Cameroon.ORCID 0000-0002-8949-7150
Elias Nchiwan NukenineDepartment of Biological Sciences, Faculty of Science, University of Ngaoundere, Ngaoundere, Cameroon.
Baolei JiaXianghu Laboratory, Hangzhou, 311231, China.ORCID 0000-0001-6434-5604
Yanlai YaoXianghu Laboratory, Hangzhou, 311231, China.ORCID 0000-0003-4086-2556
Chang-Ying NiuCollege of Plant Science & Technology, Huazhong Agricultural University, No. 1 Shizishan Street, Wuhan 430070, China.ORCID 0000-0003-2793-1422

Funding

Ministry of Higher Education of Cameroon 26/048/MINESUP/SG/CS/CEA2Ministry of Science and Technology of China through the Talented Young Scientist Program Cameroon-25-001
6 · The paper itself

Abstract

The cowpea weevil, Callosobruchus maculatus (Fabricius) (Coleoptera: Bruchidae), is a major stored-product pest. Resistance to synthetic insecticides such as dichlorvos (DDVP) has prompted interest in alternatives with distinct modes of action. This study compared multigenerational transcriptional responses of C. maculatus to DDVP and the botanical insecticide Lippia adoensis (Hochst. ex Walp.) (Lamiales: Verbenaceae) essential oil (EO). DDVP exposure was associated with progressive fitness recovery across generations, together with upregulated expression of detoxification-related genes (e.g. Cyp6g1-2, Cyp6g1-3, Gst, Est2, Pod) and cholesterol metabolism-related genes (e.g. Dhcr24-1, Dhcr24-3). In contrast, L. adoensis EO was associated with consistently higher mortality and did not elicit comparable transcriptional changes in these gene sets. Clustering patterns placed EO-treated populations closer to controls, with less evidence of the DDVP-associated expression pattern. An antagonistic index comparing treatment-related fold changes indicated an opposing transcriptional relationship between EO and DDVP. Overall, the findings are consistent with L. adoensis EO acting without inducing the DDVP-associated detoxification expression pattern, suggesting a distinct transcriptional profile that may inform botanical-based approaches to pest management.

Indexed as

DichlorvosGene ExpressionInsecticidesLippiaOils, VolatileWeevilsAnimalsColeopteraLarvaDichlorvosInsecticidesOils, VolatileCallosobruchus maculatusdetoxification enzymeDichlorvosenzymes de détoxicationessential oilhuiles essentielleréponse transcriptionnelletranscriptional response

Identifiers

PMID42811420
PMCPMC13623516

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.