Evidence map›Paper›PMID 42811166›Full record

ArticleNature metabolism2026

Size-dependent plastic exposure disrupts macrophage function and tissue-specific metabolism.

Nikola Makdissi, Maria Francesca Viola, Lisa Maria Steinheuer, Nelli Blank-Stein, Ronja Kardinal, Fabrizio Musacchio, Eliana Franco Taveras, Virginia Aliprandi, Katharina Sieckmann, Akram Abdulkadyrov and 23 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Nikola Makdissi *Developmental Biology of the Immune System, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.ORCID http://orcid.org/0000-0002-9345-038X
Maria Francesca Viola *Developmental Biology of the Immune System, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.ORCID http://orcid.org/0000-0003-0660-9506
Lisa Maria SteinheuerInstitute of Experimental Oncology, Biomathematics Division, University of Bonn, University Hospital Bonn, Bonn, Germany.
Nelli Blank-SteinDevelopmental Biology of the Immune System, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
Ronja KardinalInstitute of Innate Immunity, Biophysical Imaging, University of Bonn, University Hospital Bonn, Bonn, Germany.ORCID http://orcid.org/0009-0004-3649-2024
Fabrizio MusacchioNeuroimmunology and Imaging Group, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.ORCID http://orcid.org/0000-0002-9043-3349
Eliana Franco TaverasDevelopmental Biology of the Immune System, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.ORCID http://orcid.org/0009-0009-2227-6765
Virginia AliprandiDevelopmental Biology of the Immune System, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
Katharina SieckmannInstitute of Innate Immunity, Biophysical Imaging, University of Bonn, University Hospital Bonn, Bonn, Germany.
Akram AbdulkadyrovDevelopmental Biology of the Immune System, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
Marina L MayerDevelopmental Biology of the Immune System, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
Marie-Louise Diefenbach-WilkeDevelopmental Biology of the Immune System, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
Diana FinkInstitute of Innate Immunity, Department of Systems Immunology and Proteomics, University of Bonn, Medical Faculty, Bonn, Germany.
Hannes BeckertMicroscopy Core Facility, University of Bonn, Medical Faculty, Bonn, Germany.
Stefan BöhmdorferInstitute of Chemistry of Renewable Resources, Department of Natural Sciences and Sustainable Resources, BOKU University, Tulln, Austria.
Quentin DeveuveDivision of Genetics, Department of Biology, Friedrich Alexander University Erlangen-Nürnberg, Erlangen, Germany.
Frederike J GraelmannDevelopmental Biology of the Immune System, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.ORCID http://orcid.org/0000-0002-6265-3547
Katharina MauelDevelopmental Biology of the Immune System, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.ORCID http://orcid.org/0009-0007-4879-032X
Nele KronauDevelopmental Biology of the Immune System, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.ORCID http://orcid.org/0009-0001-4147-8719
Jake ThomasBiology of Inflammation, Life and Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.ORCID http://orcid.org/0000-0003-0526-4470
David BejaranoBiology of Inflammation, Life and Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.ORCID http://orcid.org/0000-0001-7804-0131
Andreas SchlitzerBiology of Inflammation, Life and Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.ORCID http://orcid.org/0000-0001-7662-3712
Sandra HöglerClinical Institute of Pathology, Department for Experimental and Laboratory Animal Pathology, Medical University of Vienna, Vienna, Austria.
Mohamed H YaghmourBiochemistry & Cell Biology of Lipids, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
Joerg HeerenDepartment of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0002-5647-1034
Christoph ThieleBiochemistry & Cell Biology of Lipids, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.ORCID http://orcid.org/0000-0001-5161-2558
Lukas KennerClinical Institute of Pathology, Department for Experimental and Laboratory Animal Pathology, Medical University of Vienna, Vienna, Austria.ORCID http://orcid.org/0000-0003-2184-1338
Felix MeissnerInstitute of Innate Immunity, Department of Systems Immunology and Proteomics, University of Bonn, Medical Faculty, Bonn, Germany.ORCID http://orcid.org/0000-0003-1000-7989
Falk NimmerjahnDivision of Genetics, Department of Biology, Friedrich Alexander University Erlangen-Nürnberg, Erlangen, Germany.ORCID http://orcid.org/0000-0002-5418-316X
Martin FuhrmannNeuroimmunology and Imaging Group, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.ORCID http://orcid.org/0000-0001-7672-2913
Dagmar WachtenInstitute of Innate Immunity, Biophysical Imaging, University of Bonn, University Hospital Bonn, Bonn, Germany.ORCID http://orcid.org/0000-0003-4800-6332
Kevin ThurleyInstitute of Experimental Oncology, Biomathematics Division, University of Bonn, University Hospital Bonn, Bonn, Germany.ORCID http://orcid.org/0000-0002-7217-2755
Elvira MassDevelopmental Biology of the Immune System, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany. elvira.mass@uni-bonn.de.ORCID http://orcid.org/0000-0003-2318-2356

Funding

Austrian Science Fund (Fonds zur Förderung der Wissenschaftlichen Forschung) IPPTO doc.fundsAustrian Science Fund (Fonds zur Förderung der Wissenschaftlichen Forschung) P26011Austrian Science Fund (Fonds zur Förderung der Wissenschaftlichen Forschung) P29251Austrian Science Fund (Fonds zur Förderung der Wissenschaftlichen Forschung) P34781Deutsche Forschungsgemeinschaft (German Research Foundation) 272482170Deutsche Forschungsgemeinschaft (German Research Foundation) 432325352Deutsche Forschungsgemeinschaft (German Research Foundation) 450149205Deutsche Forschungsgemeinschaft (German Research Foundation) 503306912Deutsche Forschungsgemeinschaft (German Research Foundation) 533863915Deutsche Forschungsgemeinschaft (German Research Foundation) EXC2047-390685813Deutsche Forschungsgemeinschaft (German Research Foundation) EXC2151-390873048Deutsche Forschungsgemeinschaft (German Research Foundation) GRK1873/2Deutsche Forschungsgemeinschaft (German Research Foundation) SPP2395EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) 101119427EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) 851257EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) 865618EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) P101072735European Molecular Biology Organization (EMBO) ATLF 873-2023
6 · The paper itself

Abstract

Plastic pollution is an emerging yet understudied environmental risk to the immune system. Once ingested, microplastic and nanoplastic particles (MNPs) can translocate from the gut to internal organs

Identifiers

PMID42811166

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.