Evidence map›Paper›PMID 42811163›Full record

ReviewNpj biological timing and sleep2026

From phenomenon to mechanism in the circadian clock of Synechococcus elongatus.

Susan S Golden

Abstract readReview
In one paragraph

Review in Npj biological timing and sleep, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Susan S GoldenDept. of Molecular Biology, University of California San Diego, La Jolla, CA, USA. sgolden@ucsd.edu.

Funding

Undergraduate Summer Research Experience: Molecular and cellular mechanisms of circadian timekeeping in a prokaryote modelR35GM118290 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GOLDEN, SUSAN S · 2016 to 2025
$6.7M
National Institute of General Medical Sciences, NIH R35GM118290
6 · The paper itself

Abstract

Creative and collaborative research in the early 21st century revealed the mechanistic secrets of the cyanobacterial circadian clock, a nanomachine whose function can be studied in vitro. The structural dynamics of the Synechococcus elongatus circadian oscillator, comprising KaiA, KaiB, and KaiC, establish a near 24 h cycle of activity of the global transcription regulator RpaA by rhythmically changing the interaction platform of kinases that control RpaA phosphorylation.

Identifiers

PMID42811163
PMCPMC13623876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.